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细胞凋亡机制研究进展 被引量:12

Progresses on mechanism studies for cell apoptosis
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摘要 细胞凋亡是一种重要的生物学过程,在细胞生长发育以及对外界刺激的反应中有关键的作用。就近几年细胞凋亡信号传递机制、酶学机制、线粒体在细胞凋亡中的作用以及基因调控机制的研究作一简要论述。 Cell apoptosis is an important biological process. It plays an essential role on cell growth and response for outside stimulations. This review focused on the recent advancement of apoptotic signal transduction, enzymological mechanisms, the function of mitochondria in cell apoptosis as well as the regulation of genes.
出处 《国际生物医学工程杂志》 CAS 2006年第1期45-47,64,共4页 International Journal of Biomedical Engineering
基金 天津市自然科学基金资助项目(033802911)
关键词 细胞凋亡 信号传递 线粒体 基因调控 cell apoptosis signal transduction enzymology mitochondria gene regulation
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参考文献22

  • 1Gaur U,Aggarwal BB.Regulation of proliferation,survival,and apoptosis by members of the TNF superfamily[J].Biochem Pharmacol,2003,66(8):1403-1408.
  • 2Muppidi JR,Tschopp J,Siegel RM.Life and death decisions; Secondary complexes and lipid rafts in TNF receptor family signal transduction[J].Immunity,2004,21(4):461-465.
  • 3Xu B,Bulfone-Paus S,Aoyama K,et al.Role of Fas/Fas ligand-mediated apoptosis in murine contact hypersensitivity[J].Int Immunopharmacol,2003,3(7):927-938.
  • 4Yew DT,Ping Li,Liu WK.Fas and activated caspase 8 in normal,Alzheimer and multiple infarct brains[J].Neurosci Lett,2004,26,367(1):113-117.
  • 5Concha NO,Abdel-Meguid SS.Controlling apoptosis by inhibition of caspases[J].Curr Med Chem,2002,9(6):713-726.
  • 6Dotto GP,Silke J.More than cell death:Caspases and caspase inhibitors on the move[J].Dev Cell,2004,7(1):2-3.
  • 7Thornberry NA,Lazebnik Y.Caspases:Enemies within[J].Science,1998,281:1312-1316.
  • 8Shiozaki EN,Shi Y.Caspases,IAPs,and Smac/DIABLO:Mechanisms from structural biology[J].Trends Biochem Sci,2004,29(9):486-494.
  • 9Daigle I,Simon HU.Critical role for caspases-3 and -8 in neutrophil but not eosinophil apoptosis[J].Int Arch Allergy Immunol,2001,126(2):147-156.
  • 10Shiokawa D,Shika Y,Tanuma S.Identification of two functional nuclear localization signals in DNase gamma and their roles in its apoptotic DNase activity[J].Biochem J,2003,376(Pt 2):377-381.

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