高原干部体检者高尿酸血症及相关因素的初步分析

AN ANALYSIS ON HYPERURICEMIA AND CARDIOVASCULAR RISK FACTORS AT HIGH ALTITUDE

目的 探讨高原干部体验者高尿酸血症的患病情况及与性别、年龄、相关因素的关系。方法 对青海地区干部712人进行健康体检，根据高尿酸血症诊断标准，分为高尿酸血症组及正常尿酸组，对两组性别、年龄、患病率及危险因素和相关疾病进行统计分析。结果 高尿酸血症患病率为29．07％，其中男性36．47％，女性7．22％，两者比较有显著性差异（P〈0．001），高尿酸血症患病率随年龄增长而上升，41～70岁为高发年龄段。结论 高尿酸血症存在性别和年龄差别。是发生代谢综合征的重要危险因素，应当引起高度重视。

Objective To explore the relevance of incidence of hyperuricemia to sex, age and cardiovascular risk factors in 712 examinees in high altitude. Methods 712 examinees in high altitude were divided into hyperuricemia group and normal uric acid group according to the level of uric acid. The life habits history , physical and laboratory examination were analyzed. Results The incidence of hyperuricemia was 29.07%, among which 36.4% and 7.22% were male and female respectively. There was a significant difference in female and male hyperuricemia group （ P 〈 0.05 ）. Our study also demonstrated positive relevance between the incidence of hyperuricemia and age, especially those examinees aged 41 -70 years old complicated with hypertension, high blood glucose, hypertriglyceidemia, obesity and coronary heart disease. They have the hobbies of smoking and drinking. Conclusion Hyperur - icemia, which differs in sex and age is considered as a key dangerous factors in the occurrence of metabolic syndrome.