期刊文献+

他汀类药物治疗慢性心力衰竭的非降脂作用 被引量:3

下载PDF
导出
摘要 他汀类药物是冠状动脉粥样硬化性心脏病的一级和二级预防的有效药物。目前的研究发现他汀类药物还具有许多非降脂作用,如稳定动脉粥样硬化中的不稳定斑块,促进新生血管的形成,增强血管的舒张功能等。在慢性心力衰竭中,他汀类药物还可以通过抑制炎症反应,调节免疫功能,抗氧化,改善内皮功能,调节神经体液反射,抗心室重构等作用,从而有益于患者的治疗。
作者 王云乡 何红
出处 《心脑血管病防治》 2006年第2期117-119,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
  • 相关文献

参考文献23

  • 1Ray JG, Gong Y, Sykora K, et al. Statin Use and Survival Out-tcomes in Elderly Patients With Heart Failure. Arch Intern Med,2005,165:62-67.
  • 2Futterman LG, ,Lemberg L.Statin pleiotropy:fact or fiction?Am J Crit Care, 2004, 13(3):244-249.
  • 3Kjekshus J, Pedersen TR, Olsson AG, et al. The effects of simvastatin on the incidence of heart failure in patients with coronary heart disease. J Card Fail, 1997,3(4):249-254.
  • 4Lewis SJ, Moye LA, Sacks FM, et al. Effect of pravastatin on cardio- vascular events in older patients with myocardial inffarction and cholesterol levels in the average range. Ann Intern Meal, 1998, 129(9) : 681 - 689.
  • 5Tonsoulis D, Antoniades C, Bosinakou E, et al. Effects of atorvastatin on reactire hyperemia end intlammatory process in patients with congestive heart failure. Atherosclerosis, 2005,178(2) :359 - 363.
  • 6Tonsoulis D, Antoniades C, Bosinakou E, et al. Effects of atorvastatin on reactive hyperemia end inflammatory process in patients with congestive heart failure. Atherosclerosis, 2005,178(2):359 - 363.
  • 7Fehr T,Kahlert C,Fierz W,et al .Statin-Induced Immunomodulatory Effects on Human T Cells in Vivo.Atherosclerosis, 2004, 175 (1):83-90.
  • 8Li JM, Gall NP, Grieve DJ, et al. Activatiton of NADPH oxidase during progression of cardisc hypertrophy to failure. Hypertension, 2002, 40(4) :477 - 484.
  • 9Maack C, Kartes, Kilter H, et al. Oxygen Free Radical Release in Human Failing Myocardium Is Associated With Increased Activity of Racl - GTPase and Represents a Target for Statin Treatment. Circulation, 2003, 108(13):1567-1574.
  • 10Franzoni F, Quinones- Galvan A, Regoli F, et al. A Comparative Study of the in Vitro Antioxidant Activity of Statins. Int J Carol, 2003, 90(2 - 3) :317 - 321.

同被引文献25

引证文献3

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部