医院内深部真菌感染166例分析

Analysis of 166 cases of nosocomial systemic fungus infection

报告我院１９９３年１月～１９９４年１２月，在两年的医院感染９５７例中深部真菌感染１６６例（占１７．３５％）。统计分析表明，深部真菌感染在医院感染中居重要位置。病原菌以念珠菌为主，有１２６例（占７５．９０％），其次为酵母菌和曲霉菌。感染部位以下呼吸道为主，有９３例（占５６．０２％），其次为多器官感染、菌血症等。易感因素为老年患者、长期住院的慢性消耗性疾病、恶性肿瘤、血液病、血液透析和器官移植、各种导管介入、长期应用广谱抗生素、肾上腺皮质激素和免疫抑制剂等。故提请广大医务工作者对深部真菌感染的严重性给予高度重视，合理应用抗生素，恰当应用免疫抑制剂等，旨在把深部真菌感染控制到最低限度。

This paper presents 166 cases of deeper mycosis. The percentage was 17.35% in 957 cases of nosocomial infection during the period from Jan. 1993 to Dec. 1994. The results suggest that fungi in syatemic mycosis are more important in nosocomial infection. The major pathogen are Candida spp. (75.97%). The lower respiratory tract was found to be the most common infection sites (56.02%). Most of the paticnts are elderly. Long period hospitalization and had serious comsumptive disease or aguse of antibiotics and immunosuppression. Therefore, it is necessary to encourage doctors to improve specimens culture, rational administration of antibiatics and immunosuppression. This is the most important step to control deeper mycosis infection in the hospital.