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骨立冲剂治疗脾肾两虚型原发性骨质疏松症的临床观察 被引量:3

Clinical study of Gu-li on Treating Primary Osteoporosis of Deficiency in Spleen and Kidney.
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摘要 目的:从临床的角度观察骨立冲剂改善脾肾功能、调整全身机能状况从而治疗原发性骨质疏松症(Osteo-porosis)的疗效。方法:收集符合骨质疏松症诊断标准的患者60例(男女各30例),经过三大常规、肝肾功能、血清钙磷、碱性磷酸酶(AKP)、腰椎和髋关节X线检查、骨密度检查,将60例患者按随机原则分为治疗组(骨立组)和对照组(钙尔奇组)分别进行治疗,疗程90天。治疗前后记录患者中医临床症状积分、血清钙、磷和碱性磷酸酶(AKP)的含量。疗效判定依据骨密度检测结果及中医症候积分改变。结果:治疗后两组的腰椎骨密度(BMD)均较治疗前有明显提高,髋部骨密度(BMD)均与治疗前没有明显变化。结论:骨立冲剂可提高骨质疏松患者骨密度,防止骨量丢失,从而治疗原发性骨质疏松症。 Objective: To study the effect of Gu-li on Osteoporosis (OP) of deficiency in spleen and kidney by promoting the function of spleen and kidney and adjusting the situation of body. Methods: 60 cases (male 30 and female 30) treatment group in which 30 cases were treated with Gu-Li and control group in which 30 cases were treated with Caltrate, with a course of 90 days.each case was took the routine examination of blood, routine urinalysis, hepatic function test, examination of renal function, test of calcium and phosphor of blood, examination of serum alkaline phosphatase, radiographs and examination of bone mineral density (BMD) of lumbar and hip. The scores of symptom of spleen and kidney deficiency, AKP and calcium and phosphor of blood were recorded before and after the therapeutic course. Judged the curative effect of Gu-li mostly by the changes of BMD and the scores of symptom of TCM.Results: The BMD of lumbar have increased significantly in both two groups (for male: P 〈 0.05, for female: P 〈 0.01 ) .The BMD of hip didn't get a significant increasing in both two groups (P〉0.05) .The changes in BMD have no distinct difference between Gu-li group and Caltrate group ( P 〉 0.05) .The Gu-li group excelled the Caltrate group in promoting the scores of symptom of spleen and kidney deficiency.Conclusions: We conchide that Gu-li can treat OP by increasing the BMD of the patients and preventing the osteepenia.
出处 《四川中医》 北大核心 2006年第6期75-77,共3页 Journal of Sichuan of Traditional Chinese Medicine
基金 四川省中医管理局基金资助项目(编号:200267)
关键词 原发性骨质疏松症 骨密度 脾肾两虚 骨立冲剂 Osteoparosis (OP) bone mineral density (BMD) Gu-li deficiency in spleen and kidney
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