摘要
本研究观察了赤芍对高脂兔血小板胞浆游离钙([Ca2+]i)、红细胞膜钙-镁-ATP酶(Ca2+-Mg2+-ATPase)活性血清钙及血脂的影响。结果表明:血小板[Ca2+]i含量赤芍组(276.25±27.00nmol/L)显著低于高脂组(390.88±70.00nmol/L),P<0.01;红细胞膜Ca2+-Mg2+-ATPase基础及激活活性(μmol·pi-1·mg-1·h-1)赤芍组(0.79±0.05,1.34±0.10)明显高于高脂组(0.65±0.09,1.04±0.13),P<0.01。说明赤芍可提高高脂血症兔红细胞Ca2+-Mg2+-ATP酶基础及激活活性。
The effect of Paeonia lactiflora(PL) on platelet cytosolic free calcium and erythrocyte membrane Ca2+-Mg2+-ATPase activity in hyperlipid rabbits were observed. Results showed the level of platelet cytosolic free calcium in the PL group(276.25±27.00nmol/L) was significantly lower than that in the cholesterol group(390.88±70.00nmol/L), P<0.01, the basal and calmodulin-stimulated activities of erythocyte membrane Ca2+-Mg2+-ATPase in PL group (0.79±0.05 μmol· pi-1·mg-1·h-1 and 1 .34±0.10μmol· pi-1·mg-1·h-1) were higher than that in the cholesterol group (0.65±0.09μmol·pi-1·mg-1·h-1 and 1.04±0.13μmol·pi-1·mg-1·h-1).
出处
《中国中西医结合杂志》
CSCD
北大核心
1996年第5期295-296,共2页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
赤芍
游离钙
红细胞
钙-镁-ATP酶
高血脂病
兔
Paeonia lactiflora
free calcium
erythrocyte
platelet
Ca ̄(2+)-Mg ̄(2+)-ATPase