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均匀设计法优选辅酶Q_(10)的超声提取工艺 被引量:11

Optimization of ultrasonic extraction technology for coenzyme Q_(10) based on uniform design
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摘要 用均匀设计法优化了以新鲜烟叶为原料,超声提取辅酶Q10的工艺。考察了超声时间、温度、液料比和超声功率4个因素对辅酶Q10提取率的影响,并对提取过程用多元回归方程进行了数值模拟。实验得到优化的辅酶Q10超声提取工艺条件为:提取溶剂体积分数85%乙醇,液料体积质量比18 mL/g,超声温度45℃,超声时间45 m in,超声功率250 W。结果表明,超声法提取对烟叶中辅酶Q10的提取质量分率为7.12×10-6,其提取率是索氏提取的1.34倍,实验结果与回归方程的拟合值吻合良好,说明应用超声法提取烟叶中的辅酶Q10是可行的。 An ultrasonic extraction technology of coenzyme Ql0 from tobacco (Nicotiana tabacum L. ) leaves was optimized by a uniform design experiment. The effect of ultrasonic time, temperature, ratio of liquor to material and ultrasonic power on the extraction yield of coenzyme Q10 was investigated. A mathematical simulation based on ultrasonic extraction was processed. The optimum technology parameters are: extractant volume fraction 85% ethanol, ratio of liquor to material 18 mL/g, ultrasonic temperature of 45 ℃, ultrasonic power 250 W. Under the optimized condition, the extraction mass fraction of coenzyme Q10 is 7.12 × 10^-6 by ultrasonic extraction, which means 1.34 times higher than by soxhlet extraction. The real determined values are consistent with predicted values by a regression equation. Thereby it is feasible to extract coenzyme Q10 from tobacco leaves by ultrasonic technology.
出处 《化学工程》 CAS CSCD 北大核心 2006年第6期60-63,共4页 Chemical Engineering(China)
基金 科技部科研条件升级改造资助项目(JG-2004-09)
关键词 烟叶 辅酶Q10 超声提取 均匀设计 优化 tobacco (Nicotiana tabacum L. ) leaves coenzyme Q10 ultrasonic extraction uniform design experiment optimization
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