摘要
Malaria is an important cause of death and illness in children and adults in tropical countries.Mortality,currently estimated at over a million people per year,has risen in recent years,probably due to increasing resistance to antimalarial medicines.Malaria control requires an integrated approach comprising prevention including vector control and treatment with effective antimalarials.The affordable and widely available antimalarial chloroquine which was in the past a mainstay of malaria control is now ineffective in most falciparum malaria endemic areas.and resistance to sulfadoxine-pyrimethamine is increasing rapidly.The discovery and development of the artemisinin derivatives in China.and their evaluation in south-east Asia and other regions have provided a new class of highly effective antimalarials,and have already transformed the chemotherapy of malaria in south-east Asia.Artemisinin-based combination treatments （ACTs） are now generally considered as the best current treatment for uncomplicated falc iparum malaria.
Malaria is an important cause of death and illness in children and adults in tropical countries.Mortality,currently estimated at over a million people per year,has risen in recent years,probably due to increasing resistance to antimalarial medicines.Malaria control requires an integrated approach comprising prevention including vector control and treatment with effective antimalarials.The affordable and widely available antimalarial chloroquine which was in the past a mainstay of malaria control is now ineffective in most falciparum malaria endemic areas.and resistance to sulfadoxine-pyrimethamine is increasing rapidly.The discovery and development of the artemisinin derivatives in China.and their evaluation in south-east Asia and other regions have provided a new class of highly effective antimalarials,and have already transformed the chemotherapy of malaria in south-east Asia.Artemisinin-based combination treatments （ACTs） are now generally considered as the best current treatment for uncomplicated falc iparum malaria.
