国际糖尿病联盟与中华糖尿病学会关于代谢综合征定义的比较

The comparison of the metabolic syndrome (MS) definitions between International Diabetes Federation (IDF) and Chinese Diabetes Society(CDS)

221名存在代谢综合征(MS)风险者纳入研究。平均发现的MS组分数,国际糖尿病联盟(IDF)定义比中华糖尿病学会(CDS)定义略高(2.33vs2.09,P>0.05)。二者的诊断符合率为80%。女性的MS患病率,IDF定义(18/83)高于CDS定义(2/83)(P<0.05);但男性的MS诊断率,CDS定义(18/138)高于IDF定义(7/138)(P<0.05);血糖正常者诊断有MS的患病率,IDF定义(21/94,22%)高于CDS定义(10/97,10%)(P<0.05)。CDS定义中有11例(12%)肥胖不达标者诊断MS。IDF不使用餐后血糖仅使MS漏诊6%。两种定义识别MS及其组分的能力基本相当;但与CDS定义相比,使用IDF定义能使患者群体发生以下几种漂移:从男性到女性,从糖代谢异常到脂代谢异常,从不肥胖到肥胖。

221 subjects at risk for MS were enrolled and evaluated. The discovered mean number of MS components was little greater by IDF definition than by CDS one（2.33 vs 2.09,P〉0.05）. The concordance rate of both definitions was 80% in diagnosing MS. The female MS prevalence was higher by IDF （18/83） than by CDS （2/83）（P〈0. 05）. But male MS prevalence was higher by CDS （18/138） than by IDF （7/138） （P〈0.05）. In those with normal glycaemia, more individuals were diagnosed to have MS by IDF definition （21/94,22.3%） than by CDS one （10/97,10.3%）（P〈0.05）. Of people with MS diagnosed on CDS definition, 11 （12%） were non-obese. Finally, 6% MS people was missed by IDF definition due to neglecting postprandial-challenge glycemia. In conclusions, the two definitions are comparable in identifying MS and its components, while from CDS to IDF definition some MS people drift in the way as follows： from men to women, from dysglycemia to abnormal fat metabolism, and from non-obesity to obesity.