高铁蛋白血症与糖尿病血管并发症关系的研究

The relationship between serum high-ferritin and diabetes mellitus with vascular complication

目的:探讨血清铁蛋白与糖尿病及其血管并发症的关系。方法:用化学发光法测定92例糖尿病人及50例健康对照者的血清铁蛋白水平并进行分组比较。结果:糖尿病组的血清铁蛋白水平明显高于正常对照组(P<0.01),有血管病变组明显高于无血管病变组(P<0.05),在糖尿病肾病组随着尿蛋白排泄率的增加和肾功能的恶化铁蛋白水平逐渐增高,有统计学意义。结论:血清铁蛋白与糖尿病及其血管并发症的发生有密切关系。

Objective： To study the relationship between serum ferritin and diabetes mellitus with vascular complication. Methods： The levels of the serum ferritin were measured in 92 cases with diabetes mellitus and in 50 controls. Results： The levels of the serum ferritin in diabetes mellitus were significantly higher than those in controls （P〈0.01）. The levels of the serum ferritin in diabetes mellitus with vascular complication increased significantly in comparison with diabetes mellitus without vascular complication（P〈 0.05）. Conclusion： The measurement of the serum ferritin has very important clinical value in diabetes mellitus with vascular complication.