摘要
依据石英振子的晶体谐振频率是其表面沉积物的函数，建立了简便、特异、敏感性达１００ｐｇ，并能对受检样品相对定量的核酸杂交检测新方法，即压电晶体式核酸探针传感器，该方法的主要特点是以快速。
A new nucleic acid hybridizing assay;piezoelectric quartz-sensor which is capable ofquantitative analysis has been established on thebasis that the frequency of piezoelectric quartzvibration is the function to its surface sediment.The technique is simple; specific and sensitive upto 100 pg.It uses the rapid;sensitive frequencymessages as the demonstration system of nucleicacid hybridization.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
1996年第6期527-531,共5页
Progress In Biochemistry and Biophysics
基金
国家自然科学基金
关键词
核酸杂交
生物传感器
核酸探针
nucleic acid hybridization
biosen sor
piezoelectric quartz
