新疆艾滋病患者84例临床特点分析

The clinical features of AIDS patients in Xinjiang

目的:分析新疆艾滋病患者的临床特点。方法:回顾性分析新疆地区84例艾滋病患者的流行病学特点、免疫功能及HIV相关的机会性感染特点。结果:新疆地区84例不同民族HIV阳性率不同,其中维吾尔族占73.8%;HIV感染平均年龄为32岁;感染途径主要是静脉吸毒(54.8%)及性传播(25.0%);HIV感染者中无业人员占53.6%;机会性感染中结核病占23.8%,其次为HCV/HIV和HBV/HIV的混合感染(分别为23.8%、21.4%);CD4+细胞计数<200个/mm3的HIV感染者占85.5%。结论:新疆艾滋病的主要临床特点是年轻发病多见,维吾尔族多见,大多数因静脉吸毒和性途径而感染;结核病、HCV/HIV和HBV/HIV的混合感染是较为常见的机会性感染。首次就诊时大多数患者CD4+T细胞计数已低于200个/mm3。

Objective： To evaluate the clinical features of AIDS patients in Xinjiang. Methods： The clinical data of 84 cases of AIDS in our hospital were retrospectively analyzed. Results： The HIV positive rate of Uighur nationality is 73.80% among 84 AIDS patients in Xinjiang. The main route of transmission are via intravenous drug （54%） and unsafe sexual hehaviour （25.0%） in HIV positive people. The main opportunistic infection related with HIV are tuberculosis （23.8%） and HCV/HIV, HBV/HIV coinfection and/ or superinfection （23.8% and 21.4% respectively）. About 85.5% of cases of AIDS patients＇ CD4^＋ count were less than 200/mm^3. Conclusions： In Xinjiang, The main route of transmission of AIDS are via intravenous drug and unsafe sexual hehaviour,The main opportunistic infection related with HIV are tuberculosis and HCV/HIV, HBV/HIV coinfection and/or superinfection. Most of AIDS patients＇ CD4^＋ counts are less than 200/mm^3 when they were admitted in hospital.