期刊文献+

急性脑梗死中医辨证分型与IL-6的关系探讨 被引量:5

下载PDF
导出
摘要 目的:探讨急性脑梗死(ACI)不同证型与免疫细胞因子白介素-6(IL-6)的关系。方法:采用中风病专家经验辨证量表对30例ACI患者进行证候评分,同时利用双抗体夹心ELISA法测定其IL-6含量,再按证候评分将患者分成火热证组与非火热证组,对比2组患者IL-6的变化水平。结果:火热证组在发病的72小时内、第7天、第14天血清中IL-6均显著高于非火热证组;且2组患者在上述3个时段的血清IL-6均呈逐渐下降趋势,火热证组IL-6的下降有显著性差异。结论:IL-6的升高水平可以作为判定ACI火热证与非火热证的微观学指标。
机构地区 江苏省中医院
出处 《江苏中医药》 CAS 北大核心 2006年第9期27-28,共2页 Jiangsu Journal of Traditional Chinese Medicine
基金 江苏省中医药局课题(中管2003-020)
  • 引文网络
  • 相关文献

参考文献5

二级参考文献21

  • 1Orzylowska O, Oderfeld-Nowak B, Zaremba M, et al. Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1 beta and interleukin-6 in the rat hippocampus after transient global ischemia. Neurosci Lett, 1999, 263(1 ): 72-76.
  • 2Loddick SA, Turnbull AV, Rothwell NJ. Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat.J Cereb Blood Flow Metab, 1998, 18(2): 176-179.
  • 3Tarkowski E, Rosengren L, Blomstrand C, et al. Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke.Stroke, 1995, 26(8): 1393-1398.
  • 4Block F, Peters M, Nolden-Koch M. Expression of IL-6 in the ischemic penumbra. Neuroreport, 2000, 11 (5): 963 -967.
  • 5Suzuki S, Tanaka K, Nogawa S, et al. Temporal profile and cellular localization of interleukin-6 protein after focal cerebal ischemia in rats. J Cereb Blood Flow Metab, 1999, 19(11): 1256-1262.
  • 6Suzuki S, Tanaka K, Nagata E, et al. Cerebral neurons express interleukin-6 after transient forebrain ischemia in gerbils. Neurosci Lett,1999, 262(2): 117-120.
  • 7Yu AC, Lau LT. Expression of interleukin-1 alpha, tumor necrosis factor alpha and interleukin-6 genes in astrocytes under ischemic injury. Neurochem Int, 2000, 36(4-5): 369-377.
  • 8Matsuda S, Wen TC, Morita F, et al. Interlekin-6 prevents ischemiainduced learning disability and neuronal and synaptic loss in gerbils.Neurosci Lett, 1996, 204(1-2): 109-112.
  • 9Dihne M, Block F. Focal ischemia induces transient expression of IL-6 in the substantia nigra pars reticulata. Brain Res, 2001, 889(1-2): 165-173.
  • 10Clark WM, Rinker LG, Lessov NS, et al. Lack of interleukin-6 expression is not protective against focal central nervous system ischemia. Stroke, 2000, 31(7): 1715-1720.

共引文献33075

同被引文献73

引证文献5

二级引证文献44

;
使用帮助 返回顶部