摘要
用大剂量环磷酰胺(首次剂量8mg·kg-1/d,次日起4mg·kg-1/d,连续5d为一疗程)治疗247例格林-巴利综合征(GBS),并与同期常规剂量(2mg·kg-1/d,连续5d为一疗程)环磷酰胺单独或联合使用肾上腺皮质激素(连续7d为一疗程)及中药等治疗的88例GBS进行对照观察。结果表明,大剂量环磷酰胺对控制急性期麻痹发展,控制病型升级及减少气管切开有一定疗效,且其副反应轻微。
The results of therapeutic effect of large dose of cyclophosphamide on 247 patients with Guillain-Barre syndrome(GBS)showed that it was better than that of convertional dose of cyclophosphamide alone or combined with adrenal corticosteroids,or with traditional Chinese medicine.But,it had a little side effects.
出处
《中国神经免疫学和神经病学杂志》
CAS
1996年第3期179-181,共3页
Chinese Journal of Neuroimmunology and Neurology