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基于ADuC841的膜片钳放大器的设计 被引量:1

Design of patch clamp amplifier based on ADuC841
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摘要 为降低成本和解决现有膜片钳放大器系统中PC机的干扰问题,研究了一种基于单片机的膜片钳放大器小系统。该系统采用ADI公司生产的ADuC841作为控制核心,并且配置相应的液晶显示模块LCM3202401。模拟电路部分采用高输入阻抗的AD8627实现微电流信号的采集,并由后级电路进行信号的放大和电阻电容的补偿。它具有硬件电路简单、体积小、使用方便的特点。既可以单独作为小系统实现采集和显示,也可以通过红外方式和PC机进行通讯,在PC机上进行信号的处理。 In order to reduce cost and resolve the interferential problem with PC in existing patch clamp amplifiers, a small patch clamp amplifier system design based on microcontroller is studied. It adopts a new high performance microconverter ADuC841 by the ADI as the control core in the system, configuring a liquid crystal module LCM3202401. In the analog circuit, AD8627 with high input impedance is used to detect the low current, signal magnification, as well as resistance and capacitance compensation are accomplished by subsequent circuits. It has the advantage of simple hardware circuit design, small volume and convenient operation. It can either be used as an independent system to measure and show signal detected or transmit to PC by infrared ray.
出处 《国外电子元器件》 2006年第10期11-15,共5页 International Electronic Elements
关键词 离子通道电流 电阻电容补偿 膜片钳 ion channel current compensation of resistance and capacitance patch clamp
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参考文献4

  • 1康华光.膜片钳技术及应用[M].北京:科学出版社.2003.
  • 2任继红,韦顺会,瞿安连.PC-Ⅲ 型膜片钳放大器自动电容补偿的实现[J].华中理工大学学报,1998,26(5):27-29. 被引量:2
  • 3冈田泰伸 小原正裕.膜片钳技术的原理和操作[J].日本生理学杂志,1995,56:133-133.
  • 4F. J. Sigworth. Design of the EPC-9, a computer controlled patch-clampamplifier. 1. Hardware [J].Journal of Neuroscience Methods, 1995 (56):195-202.

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