肝素联合阿司匹林治疗抗磷脂综合征

Combined heprinar and aspirin treatment for patients with antiphospholipid syndrome

目的:探讨肝素联合阿司匹林治疗抗磷脂综合征的疗效。方法:分析42例患者治疗前后的情况。结果:统计学分析表明,42例抗磷脂综合征患者治疗后,不孕症及胎儿宫内发育迟缓较治疗前有显著性差异,习惯性流产、早产、胎死宫内和妊娠高血压综合征与治疗前相比无显著差异。结论:肝素联合阿司匹林治疗抗磷脂综合征安全有效。

Objective： To study the therapeutic efficacy of combined heprinar and aspirin for patients with antiphospholipid syndrome （APS）. Methods： Form April 2000 to July 2003,42 patients with APS were treated by heprinar combined with aspirin. Their curative effects and follow -up results were analyzed. Results： The incidence rates of infertility and intrauterine growth retardation were significantly lower after treatment than those before treatment （ P 〈 0.05 ）, and the incidence rates of habitual abortion, premature delivery, fetal death and pregnancy- induced hypertension syndrome were not markedly different after treatment compared with before treatment（ P 〉 0.05）. Conclusion： Heprinar treatment combined with aspirin may be a safe and effective method for patients with APS.