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Cystatin C-检测肾小球滤过率的一项重要指标 被引量:2

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摘要 目的探讨半胱氨酸蛋白酶抑制剂C(Cys-C)在评价肾小球滤过率的临床意义。方法用微粒子增强比浊法检测129例肾病患者半胱氨酸蛋白酶抑制剂C(Cys-C)的浓度,同时用7170日立全自动生化仪检测血清尿素氮、肌酐、肌酐清除率相比较。结果发现尿素氮、肌酐、肌酐清除率与Cys-C均有相关性,相关系数为0.72、0.77、-0.80,Cys-C的灵敏度和特异性分别为83.4%、90.4%。对肾功能治疗前、后的追踪观察,Cys-C比BUN、Scr更能真实的反映出肾功能的恢复情况。结论半胱氨酸蛋白酶抑制剂C(Cys-C)是一种较理想的反映肾小球滤过率的指标。
出处 《江西医学检验》 2006年第5期439-440,共2页 Jiangxi Journal of Medical Laboratory Sciences
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