期刊文献+

四种植骨材料对血小板粘附的实验研究

An Experimental Research of Platelet-Rich Plasma(PRP) Adhesion to Four Bone Substitutes
下载PDF
导出
摘要 目的:检测四种口腔种植临床常用植骨材料对血小板的粘附能力。方法:分别将Bio-oss、PepGen-15、Algipore和Perioglas加入人PRP,在37℃水浴中分别放置10min、20min和30min,计算血小板粘附数目及四种材料和PRP混合最佳时间,并计算单位重量材料粘附血小板数;同时用环境扫描电镜验证四种材料粘附血小板的情况。结果:PepGen-15粘附血小板的性能最好;Perioglas、Bio-oss和Algipore三者之间未显示统计学差异。结论:不同植骨材料粘附血小板的能力不同,临床应根据其粘附特性决定患者取血量和最佳混合时间。 Object: To detect and research the capability of PRP adhesion to the four ordinary bone-substitutes in dental implant clinic. Method: Four bone-substitutes ( Bio-oss, PepGen-15, Algipore and Perioglas) were chosen in this experiment. Every material was placed into the water(37℃) with PRP for 10min,20min and 30min respectively, to detect the capability of PRP adhesion to the four bone-sub- stitutes with environmental scanning electron microscopy(ESEM); to explore the best time when the ma- terial and PRP were mixed; and to calculate the number of PRP adhesion to per gram bone-substitute. Result: PepGen-15 has the best capability of adhesion to PRP among the four bone-substitutes, the others have no statistical difference. Conclusion: The capabilities of PRP adhesion to the four bonesubstitutes are different. In the clinical use, we should decide the quantity of patients' blood needed and the mixed time according to the different materials.
出处 《中国口腔种植学杂志》 2006年第3期101-103,109,共4页 Chinese Journal of Oral Implantology
基金 上海市科委启明星培养计划(03QD14056)
关键词 植骨材料 富血小板血浆 血小板粘附 Bone-substitute Platelet-Rich Plasma(PRP) Platelet adhesion
  • 引文网络
  • 相关文献

参考文献17

  • 1Dugrillon A,Eichler H,Kern S,et al.Autologous concentrated platelet-rich plasma (cPRP) for local application in bone regeneration.Int J Oral Maxillofac Surg,2002,3 (6):615-619
  • 2Marx RE,Carlson ER,Eichstaedt RM,et al.Platelet-rich plasma:crowth factor enhancement for bone grafts.Oral Surg Oral Med Oral Pathol Oral Radiol Endod,1998,85 (6):638-646
  • 3王学锋,王鸿利.血栓与止血检测的常用试剂,血栓与止血的检测及应用.上海:世界图书出版上海公司,2002,38-39
  • 4Woo VV,Chuang SK,Daher S,et al.Dentoalveolar reconstructive procedures as a risk factor for implant failure.Oral Maxillofac Surg,2004,62 (7):773-780
  • 5Berglundh T,Lindhe J.Healing around implants placed in bone defects treated with Bio-Oss:An experimental study in the dog.Clin Oral Implants Res,1997,8 (2):117-124
  • 6Schepers E,Barbier L,Ducheyne P.Implant placement enhanced by bioactive glass particles of narrow size range.International Journal of Oral and maxillofacial implants,1998,13 (5):655-665
  • 7Aghaloo TL,Moy PK,Freymiller EG.Evaluation of platelet-rich plasma in combination with anorganic bovine bone in the rabbit cranium:a pilot study.Int J Oral Maxillofac Implants.2004,19 (1):59-65
  • 8范伟杰,汤继文,徐雪梅.PerioGlas骨骼肌内、骨内种植组织形态学评价[J].实用口腔医学杂志,2003,19(6):576-579. 被引量:2
  • 9Yahya Alil12*,Hendrik Terheyden 1,Anton Dunsche,et al.Three-dimensional cultivation of human osteoblast-like cells on highly porous natural bone mineral.Journal of Biomedical Materials Research,2000,51 (4):703-710
  • 10Pinholt EM,Bang G,Haanaes HR.Alveolar ridge augmentation in rats by Bio-Oss.Scand J Dent Res,1991,99:154-161

二级参考文献54

  • 1郑际烈,沈伟侠.脱矿骨及其提取物(骨形成蛋白)诱导骨形成的实验研究[J].中华口腔医学杂志,1989,24(2):78-81. 被引量:1
  • 2[2]Pazzaglia UE,Gabbi C,Locardi B,et al. Study of the osteoconductive properties of bioactive glass fibers.J Biomed Mater Res, 1989, 23(11):1289
  • 3[3]Virolainen P, Heikkila J, Yli-Urpo A, et al. Histomorphometric and molecular biologic comparison of bioactive glass granules and autogenous bone grafts in augmentation of bone defect healing. J Biomed Mater Res, 1997,35(1):9
  • 4[4]Keeting PE,Oursler MJ,Wiegand KE, et al. Zeolite A increase proliferation,defferentiation, and transforming growth factor β production in normal adult human osteoblast-like cells in Vitro. J Bone Miner Res, 1992,7(11):1281
  • 5[5]Maroothynaden J,Hench LL. Bioglass: stimulation of embryonic long bones in altered loading environments.J Gravit Physiol,2001,8(1):79
  • 6Anitua E. Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants, 1999,14(4):529.
  • 7Fennis JP, Stoelinga PJ, Jansen JA. Mandibular reconstruction:a clinical and radiographic animal study on the use of autogenous scaffolds and platelet-rich plasma. Int J Oral Maxillofac Surg,2002;31(3) :281.
  • 8Froum SJ, Wallace SS, Tarnow DP,et al. Effect of platelet-rich plasma on bone growth and ossteointegration in human maxillary sinus grafts: Three bilateral case reports. Int J Periodontics Restorative Dent, 2002,22(1):45.
  • 9Tischler M. Platelet rich plasma. The use of autologous growth factors to enhance bone and soft tissue grafts. NY State Dent J,2002,68(3) : 22.
  • 10Tayapongsak P, O Brlnen DA, Monteiro CB, et al. Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow. J Oral Maxillofac Surg, 1994,52(2):161.

共引文献99

相关主题

;
使用帮助 返回顶部