185例急性甲戊黄疸型肝炎血清流行病学及其临床特点

Seroepidemilogy and its clinical characteristic from patients with acute bilious peneumonia of hepatitisAE

对１８５例急性黄疸型病毒性肝炎的病原学分析，同时观察甲、戊及甲戊重叠感染者的临床特点，结果为：甲肝占３７３％，戊肝占２０５％。甲戊肝占８１％，老年戊肝显著高于非老年者。戊肝发热发生率显著低于甲或甲戊肝；戊及甲戊肝淤胆症状发生率平均ＡＬＰ及ＧＧＴ显著高于甲肝；甲戊肝炎哎吐及上腹痛发生率，平均ＡＬＴ、ＡＳＴ及ＴＢｉｌ显著高于甲或戊肝；Ｂ超显示肝者胆囊壁边比例异常率及透声差比甲肝多见；三种肝炎均有少部分门、脾静脉扩张者。提示：北京地区急黄疸肝炎中ＨＡＶ感染是主要病因，ＨＥＶ是次要病因，老年ＨＥＶ感染率同。戊肝、甲戊肝淤胆症状比甲肝明显多见；甲戊肝症状及肝功损害较甲肝或戊肝重；三种肝炎均可致门脾静脉暂时性扩张。

The analysis of etiology from 185 Patients with acute icteric viral hepatitis has been conducted and the clinical characteristic from patients infected by hepatitisA or hepatitisE or by overlapped ones was also observed. Results showed that the percentage of hepatiitisA was 37 3%, hepatitisE 20 5%, hepatitisAE8 1%. and the old people suffered from hepatitisE was obviously higher than the youth. The incidence rate of fever in hepatitisE was obviously lower than hepatitisA or hepatitisAE, and the incidence rate of cholestatic symtom in hepatitis AE (the average of ALP and GGT)was obviously highex than hepatiisA, and the incidence rate of vomit and epigastralgia in hepatitis AE (the average of ALT, AST and TBil)was obviously higher than hepatitisA or E. It was shown in ultrasound that the abnormity rate of the margin of gallbladder was often observed in patients with hepatitis E than in hepatitisA. All the patients suffered from pylephlebectasis and dilation of splenic vein. It indicated that HAV infection was the main reason to cause acute, icteric hepatitis, HEV wasthe minor one, HEV infected rate was higher in the old man.