130例原发泪腺上皮性肿瘤的诊断分析

Diagnosis of 130 cases with epithelial tumors of lacrimal gland

目的分析130例泪腺上皮性肿瘤临床特点,明确诊断依据。设计回顾性病例系列。研究对象130例原发泪腺上皮性肿瘤。方法收集130例经病理检查确诊的泪腺上皮性肿瘤的临床资料、影像学资料和组织病理学资料。主要指标临床表现,影像学表现,组织病理学表现。结果泪腺上皮性肿瘤临床表现主要为眼球突出、视力下降、疼痛、复视等。良性肿瘤中以多形性腺瘤(43．8％)为多,恶性肿瘤占前三位的分别为腺样囊性癌(38．5％),恶性混合瘤(8．5％),腺癌(3．8％)。眼眶B超、CT、MRI都有典型的影像学特征。组织病理学改变是最终诊断依据。结论将影像学表现和临床资料结合起来可对泪腺上皮性肿瘤作出初步诊断,最终诊断要依靠组织病理学检查。

Objective To analyse the clinical characteristics of 130 cases with epithelial tumors of lacrimal gland and identify the diagnosis. Design Retrospective case series study. Participants 130 cases with epithelial tumors of lacrimal gland. Methods Clinical, imaging and histopathological data of 130 cases with tumors of lacrimal gland from Institute of Orbital Diseases, General Hospital of Chinese People＇s Armed Police Forces were analyzed. Main Outcome Measures Clinical, imaging and histopathological manifestations. Results The main clinical manifestations of epithelial tumors of lacrimal gland were ocular proptosis, vision degression, soreness and diplopia etc. The most common kind of benign tumor was pleomorphic adenoma （43.8%）. The top three kinds of malignant tumors were adenoid cystic carcinoma （38.5%）, pleomorphic adenocarcinoma （8.5%）and adenocarcinoma （3.8%）. Each kind of the tumors has its special B scan, CT, MRI imaging characters. Conclusion It is very important for primary diagnosis with a combination of clinical and imaging appearances, but the final diagnosis depends on the histopathological data.