期刊文献+

心肌细胞再生与细胞移植

下载PDF
导出
摘要 成年心肌细胞并非终末分化细胞,通过细胞增殖与更新维持心肌细胞动态平衡及修复损坏心肌。再生心肌细胞可能来源于心肌干细胞,而干细胞则来源于体循环而非心脏本身。移植于心肌内的骨髓干细胞可分化为具有功能的心肌细胞及血管,替代瘢痕组织及改善心脏功能。
机构地区 北京
出处 《中国分子心脏病学杂志》 CAS 2002年第5期50-52,共3页 Molecular Cardiology of China
  • 相关文献

参考文献25

  • 1[1]Soonpaa MH, Field LI. Survey of studies examining mammalian cardiomyocyte DNA synthesis. Circ Res, 1998, 83:15-26.
  • 2[2]Anversa P, Kajstura J. Ventricular myocytes are not terminally differentiated in the adult mammalian heart. Circ Res, 1998,83: 1-14.
  • 3[3]Kajstura J, Leri A, Finato N, et al. Myocyte proliferation in end-stage cardiac failure in humans. Proc. Natl Acad. Sci.USA, 1998, 95: 8801-8805.
  • 4[4]Beltrami AP, Urbanek K, Kajstura J, et al. Evidence that human cardiac myocytes divide after myocardial infarction. N.Engl. J. Med., 2001, 344:1750-1757.
  • 5[5]Anversa P, Leri A, Kajstura J, et al. Myocyte growth and cardiac repair. J Mol Cell Cardiol, 2002, 34:91-105.
  • 6[6]Leri A, Malhotra A, Liew CC, et al. Telomerase activity in rat cardiac myocytes is age and gender dependent. J. Mol.Cell. Cardiol., 2000, 32: 385-390.
  • 7[7]Leri A, Barlucchi L, Limana F, et al. Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart. Proc Natl Acad Sci U S A, 2001, 98: 8626-8631.
  • 8[8]Kajstura J, Zhang X, Reiss K, et al. Myocyte cellular hyperplasia and myocyte cellular hypertrophy contribute to chronic ventricular remodeling in coronary artery narrowing induced cardiomyopathy in rats. Cire Res, 1994, 74:383-400.
  • 9[9]Teyssier-Le Discorde M., Prost S., Nandrot E, et al. Spatial and temporal mapping of c-kit and its ligand, stem cell factor expression during human embryonic haemopoiesis. Br. J.Haematol, 1999, 107:247-253.
  • 10[10]Kunisada T, Yoshida H, Yarmazaki H, et al. Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors. Development, 1998, 125: 2915-2923.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部