上海市社区癌症患者抑郁状况及其影响因素研究

Study on the prevalence of depression among cancer patients and its influencing factors in Shanghai

目的了解上海市社区癌症患者抑郁流行状况及其影响因素。方法采用整群抽样的方法从上海肿瘤病例数据库中选取社区中7967例癌症患者进行问卷调查并填写自评量表，共回收合格调查表6694份。统计描述其抑郁状况的流行病学分布，使用条件logistic回归分析数据，确定患者发生抑郁的主要影响因素。结果社区癌症患者中，抑郁发生的比例为24．74％（95％CI：23．71％～25．79％）。患者生存期、诊断时期别、肿瘤有否转移、治疗状况、体能评分KPS、疼痛VAS评分是抑郁发生的主要影响因素。结论早期诊断癌症、提高临床治疗效果、提供社区康复指导与服务可降低社区癌症患者抑郁的发生比例。

Objective To determine the prevalence of depression among cancer patients and its influencing factors. Methods We investigated 7967 cancer patients who lived in communities with cluster sampling based on ‘Shanghai Cancer Patient Database＇. They were investigated through questionnaires and completed the Zung Self-rating Scale. 6694 questionnaires were identified as ‘qualified＇. We calculated the prevalence of depression and determined the factors with logistic regression model. Results The prevalence rate of depression among cancer patients in communities was 24.74 % （ 95 % CI ： 23.71% - 25.79 % ）. Results from multi-factor analysis showed that duration since diagnosis, stages at diagnosis, metastasis, therapeutics, KPS scores, and pain VAS scores were the important factors. Conclusion Early detection, improving the curative effect and providing community health services could reduce the prevalence of depression.