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中医药抗肝纤维化研究的现状和展望 被引量:34

Present Situation and Prospects or the Studies or treating Hepatic Fibrosis by TCM Therapies
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摘要 从肝纤维化形成机理、中医药抗肝纤维化的研究、抗肝纤维化的实验研究及展望4个方面,就肝纤维化的防治研究进行了评述。认为探索抗肝纤维化的方药,应统一在防治慢性肝病的总目标中,活血化瘀方药应视为探索的重点课题;同时应加强与人类肝纤维化相似的动物模型的研制,建立客观性、特异性的检测指标,并从分子生物学的角度研究病变的机理。 The paper reviews the studies on prevention and treatment of hepatic fibrosis from four aspects or pathogenesis of hepatic fibrosis, studies of treating hepatic fibroeis by TCM therapies, laboratory studies of resisting hepatic fibrosis, and prospects of treating hepatic fibrosis. The author holds that the exploratory research on TCM recipes and drugs against hepatic fibrosis should be included in the overall object of preventing and treating chronic hepatic diseases, and the recipes and drugs used to promote blood flow for eliminating blood stasis should be regarded as key subjects in the exploratory research. The author believes that studies of treating hepatic fibrosis will achieve significant results on the basis of designing the animal model of hepatic fibrosis which resembles that in human beings, establishing objective and specific test criteria, and studying the pathogenesis of hepatic fibrosis on molecular biological level.
作者 贲长恩
出处 《北京中医药大学学报》 CAS CSCD 1996年第5期2-8,共7页 Journal of Beijing University of Traditional Chinese Medicine
关键词 肝纤维化 中医药疗法 动物模型 Hepatic Fibrosis TCM Experimental Study Animal Model
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