伊莎笼养蛋鸡骨代谢的增龄性改变

Age-related changes of bone metabolism in ISA layers

研究了15、35、58和70周龄伊莎(ISA)笼养蛋鸡骨代谢变化规律。试验结果显示:与15周龄比较,70周龄ISA蛋鸡的碱性磷酸酶(AKP)和抗酒石酸酸性磷酸酶(StrACP)水平分别下降61.06%和54.38%(P<0.05);肱骨、胫骨、股骨和龙骨的放射密度分别增加35.23%、34.86%、28.38%和34.86%(P<0.05);而肱骨、胫骨和股骨的平均皮质骨宽度分别下降11.43%、36.96%和28.75%(P<0.05),皮质骨面积百分率分别下降13.97%、38.02%和28.53%(P<0.05)。表明:70周龄ISA蛋鸡骨形成减弱,骨吸收增加,已发生显著的骨质疏松症。皮质骨在产蛋周期的持续性重吸收是笼养蛋鸡骨质疏松症的重要成因之一。

The changes of bone metabolism in ISA layers with 15, 35, 58 and 70 week-age were reported in this paper. The resuits were as follows： compared with the 15 week-age group, AKP and StrACP levels in 70 week-age group decreased 61.06% and 54. 38% （P 〈0. 05）, respectively; the radiographic density of humerus, tibia, femur and keel increased 35.23%, 34. 86%, 28. 38% and 34. 86% （P 〈0. 05）, respectively; and the cortical width of humerus, tibia and femur in 70 week-age group decreased 11.43%, 36. 96% and 28.75 % （P 〈 0.05 ）, respectively, percentage of cortical volume decreased 13.97%, 38.02% and 28. 53% （P 〈0.05）, respectively. In conclusion, the bone formation was decreased while its resorption was increased in 70 weeks-age ISA layers with severe osteoporosis. It is one of important factors that continued resorption of cortical bone leads to osteoporosis throughout the laying period.