宁心颗粒治疗小儿病毒性心肌炎30例临床观察

Ningxin Granule for Pediatric Viral Myocarditis:A Clinical Observation of 30 Cases

目的观察宁心颗粒治疗小儿病毒性心肌炎的临床疗效。方法将60名患儿随机分为治疗组和对照组各30例,两组在性别、年龄、病情等方面差异无显著性意义。治疗组采用宁心颗粒口服;对照组采用能量合剂三磷腺苷(ATP)、辅酶A、维生素C、肌苷及病毒唑静脉滴注。结果治疗组在缓解临床症状、减少早搏、降低肌酸激酶同工酶(CK-MB)、心肌肌钙蛋白(cTnI)及增高左心室的射血分数,缩小患儿扩大的左室内径等方面,疗效优于对照组。结论宁心颗粒具有明显缓解病毒性心肌炎患儿的症状、体征,减少早搏发生次数,降低异常升高的心肌酶学指标及改善左心功能的作用。

Objective To observe the therapeutic effect of Ningxin Granule Heart-Quieting Granule for pediatric viral myocafditis. Methods Totally 60 cases of pediatric viral myocarditis were randomly divided into treatment group （n = 30） and control group （n= 30）. There was no significant difference between two groups in sexuality ,age and pathogenetic condition. Patients in treatment group took Ningxin Granule,while ATP,CoA,Vit C,Inosine and Ribavirin were given to control group by intravenous drip. Results The treatment group was superior to control group in relieving symptoms,reducing the bearing premature,CK-MB,cTnI and LVEDD,and increasing LVEF. Conclusion Ningxin Granule can obviously relieve symptoms and signs,reduce the bearing premature,decrease the level of myocardial enzyme and improve the cardiac function.