摘要
目的:比较不同性别及不同静息心率的健康体检者腰围、血压水平、空腹血糖和餐后2h血糖、三酰甘油及高密度脂蛋白胆固醇水平的差异。方法:①选择2003-06/2005-10在广西医科大学第五附属医院干部保健中心进行健康体检者1014名,男658名,女356名,年龄35~50岁。均对检测指标知情同意。按静息心率水平将纳入对象分为3组:静息心率<70次/min组(n=305),70次/min≤静息心率<79次/min组(n=437),静息心率≥80次/min组(n=272)。②测量纳入对象血压、腰围、血清总胆固醇、三酰甘油、高密度脂蛋白胆固醇、空腹血糖、餐后2h血糖水平。以5.60mmol/L≤空腹血糖<7.0mmol/L为空腹血糖异常;以7.8mmol/L≤餐后2h血糖<11.1mmol/L为糖耐量低减;以非同日2次空腹血糖≥7.0mmol/L和/或餐后2h血糖≥11.1mmol/L为糖尿病。③分别采用t检验和χ2检验对计量资料和计数资料进行统计学处理。结果:健康体检者1014名均进入结果分析。①血压变化:男性静息心率最高和最低组血压比较,静息心率≥80次/min组与70次/min≤静息心率<79次/min组男性舒张压比较,差异明显(t=2.01~2.44,P<0.05);静息心率<70次/min组与其他2个静息心率组女性收缩压比较,静息心率最高和最低组舒张压比较,差异明显(t=1.98~2.63,P<0.05~0.01)。②血糖水平变化:男女性空腹血糖均随静息心率增加而逐渐增高。静息心率≥80次/min组男女性餐后2h血糖水平均明显高于其他2个静息心率组(t=2.15~2.59,P<0.05~0.01),其中女性体检者餐后2h血糖水平随静息心率的增加而逐渐增高。③血清三酰甘油水平变化:男女性三酰甘油水平均随静息心率增加而逐渐增高,其中静息心率≥80次/min组男性明显高于其他2个静息心率组(t=2.72,2.00,P<0.01,0.05)。④血清高密度脂蛋白胆固醇水平变化:男性血清高密度脂蛋白胆固醇水平随静息心率增加而逐渐降低。⑤腰围:各静息心率组间差异不明显。结论:不同静息心率男性体检者间血清高密度脂蛋白胆固醇水平存在明显差异;男女性血压水平、空腹血糖、血清三酰甘油水平存在明显差别;女性体检者餐后2h血糖也存在明显差异。
AIM: To compare waist circumference (WC), the level of blood pressure (BP), fasting blood glucose (FBG), blood glucose after meal two hours (2hPBG), triglyceride (TG) and high density lipoprotein-cholesterol (HDL-C) in healthy examinees with different resting heart rate (RHR) and either gender. METHODS: (1)A total of 1 014 healthy examinees aged 35-50 years was selected from Center of Healthy Care for Cadres, Fifth Affiliated Hospital, Guangxi Medical University from June 2003 to October 2005, including 658 males and 356 females. With their informed consents of detection indexes, they were divided into three groups according to the levels of RHR: RHR1 group (n =305): RHR 〈 70 beats per minute (bpm); RHR2 group (n =437): 70 bpm ≤ RHR 〈 79 bpm; RHR3 group (n =272): RHR ≥ 80 bpm.(2)The BP, WC, levels of total cholesterol (TC), TG, HDL-C, FBG and 2hPBG of subjects were measured. Abnormal FBG: 5.60 mmol/L ≤ FBG 〈 7.0 mmol/L; Impaired glucose tolerance: 7.8 mmol/L ≤2hPBG 〈 11.1 mmol/L; Diabetes mellitus: Two levels of FBG in different days ≥ 7.0 mmol/L and/or 2hPBG ≥ 11.1 mmol/L. (3)The measurement data and numeration data were statistically analyzed with t test and x^2 test respectively. RESULTS: All the 1 014 healthy examinees were involved in the result analysis,(1)BP: There were obvious differences in the BP of men between RHR3 group and RHR1 group, and diastolic BP of men between RHR3 group and RHR2 group (t =2.01-2.44, P 〈 0.05); And there were also obvious differences in the systolic BP of women between RHR1 group and other 2 groups, and in the diastolic BP of women between RHR1 group and RHR3 group (t =1.98-2.63, P 〈 0.05-0.01). (2)Blood glucose: With RHR raised, the FBG increased gradually for both men and women, and 2hPBG of women also increased gradually; RHR3 group showed significantly higher level of 2hPBG than other two groups (t =2.15-2.59, P 〈 0.05-0.01). (3)TG: TG levels of both men and women were elevated gradually with RHR increased, and men of RHR3 group presented significantly higher level than other two groups (t =2.72, 2,00, P 〈 0,01, 0.05).(4)HDL-C: Serum HDL-C level of men decreased gradually with the increase of RHR. (5)WC: There was no marked difference among three RHR groups. CONCLUSION: Male healthy examinees with different RHRs show significantly different serum HDL-C levels; There are significant differences in levels of BP, FBG and TG between men and women; And 2hPBG level presents statistical significance in female healthy examinees.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2007年第12期2351-2353,共3页
Journal of Clinical Rehabilitative Tissue Engineering Research