急性脑梗死患者血清钙和镁浓度变化及临床意义

The Changes of Serum Calcium and Magnesium in Acute Cerebral Infarction Patients and Its Clinical Significance

目的探讨血清钙、镁浓度与急性脑梗死的关系及其临床意义。方法检测220例急性脑梗死患者发病72h内血清钙、镁浓度,并对患者进行临床神经功能缺损程度评分,分为轻(A组)、中(B组)、重型脑梗死(C组)3组。并以42例同期健康者为对照组。比较3组患者及与对照组血清钙、镁浓度。结果脑梗死患者与对照组研究对象血清钙、镁浓度间差异有显著性意义(P<0.01),并且A、B、C3组患者血清钙、镁浓度间差异亦均有显著性意义(P<0.01)。结论急性脑梗死患者血清钙、镁浓度降低,且其降低程度与临床神经功能缺损程度评分相关。

Objective To observe changes of serum magnesium and calcium in the patients with acute cerebral infarction and elucidated its clinical significance. Methods We examined the concentrations of serum magnesium and calcium in 72 hours after the onset was determined in 220 patients who were diagnosed with acute cerebral infarction stroke, calculated the clinical nerve deficiency scale in every patient and divided the patients into mild cerebral infarction （ group A）, moderate cerebral infarction （ group B）, and severe cerebral infarction （group C） according to the scale, 42 healthy controls. Comparison the concentrations of serum magnesium and calcium in the four groups. Results The concentration of serum calcium and magnesium in patients was decreased significantly when compared with the control group （ P 〈 0. 01 ）, The concentration of serum calcium and magnesium was different between the group A, B, C （P 〈0.01）, Conclusion The concentration of serum calcium and magnesium in acute cerebral infarction is decreased, and the degree of decrease was related with the clinical nerve deficiency scale.