老年人住院用药现状及其相关因素分析

Current situation of medication and analysis of their correlation factors in the aged in-patients

目的:分析老年住院病人用药现状及相关因素,指导合理用药。方法:采用人群随机抽样研究方法对我院2006年1月～2006年10月收治住院的老年病人用药情况及其相关因素进行统计分析。结果:本组抽样获得的213例病人中,大多老年住院病人有两种或两种以上疾病,有2/3病人同时使用7种或7种以上药物治疗,其中同时使用≥10种者高达34.74%。老年住院病人使用药物数量与其所患疾病种类数、住院时间有明显相关性(P<0.05)。本组资料老年住院病人药物相关的不良反应发生率为7.98%,主要为胃肠道反应、皮疹、出血凝血时间延长及心血管系统等。结论:老年人所患疾病多、住院时间过长是造成用药种类多的重要因素,亦是极易发生药物相互作用和不良反应的主要原因。

Objective ：To analyze the current situation of medication and analysis of their correlation factors in the aged in-patients in order to guide rational administration. Methods：The current situation of medication and correlation factors in the aged in-patients ad- mitted to this hospital from January 2006 to October 2006 were analyzed by random sampling of population.Results：Of 213 elderly in-patients acquired by random sampling, a major of them suffered from two or more than two kinds of diseases, two-thirds of them were administered seven or more than seven kinds of drugs at the same time, more than ten kinds of agents accounted for 34.7%. There was obvious correlation between drug numbers administered to the aged in-patients and number of diseases or length of stay of them （P〈0.05）. The incidence rate of drug adverse reaction in these patients was 7.89%, predominantly including gastrointestinal tract reaction, rash, prolonged time of bleeding and coagulation ,cardiovascular system and so on.Conclusion：The much more kinds of diseases and long hospital time stay were the important factors to cause medication of the aged in-patients too more and the main causes that lead to occurrence of drug interactions and adverse effects.