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血清尿酸在冠心病患者中的变化及意义 被引量:3

Changes of Serum Uric Acid in Patients with Coronary Heart Disease and its Significance
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摘要 目的探讨血清尿酸水平与冠心病的关系。方法经冠状动脉造影确诊的冠心病患者(冠心病组)95例和非冠心病患者(对照组)72例,冠心病组又分为单支病变亚组(40例)、双支病变亚组(32例)和三支病变亚组(23例),均测定血清尿酸水平。结果冠心病组血清尿酸水平显著高于对照组(P<0.01),双支病变亚组和三支病变亚组血清尿酸水平均显著高于单支病变亚组(P<0.05;P<0.01)。结论血清尿酸水平与冠心病密切相关,且随冠心病病情严重程度而增加,高尿酸血症是冠心病的一个危险因素。 Objective To investigate the correlation between serum uric acid (SUA) and coronary heart disease (CHD) . Methods 95 patients with CHD proved by angiography and 72 control subjects without CHD were included in this study.The group of CHD was divided into three subgroups of single-branch, double-branch and three-branch according to the scope of pathological changes. SUA levels were measured. Results SUA levels in CHD group were significantly higher than those in control group (P〈0.01). SUA levels in double-branch subgroup and three-branch subgroup were obviously higher than those in single-branch subgroup (P〈0.05, P〈0.01). Conclusion The SUA levels have a close ralationship with CHD. The SUA levels increase along with the severity of comary heart disease. Hyperuricemia is one of risk factors in CHD.
作者 李华 卫金梅
出处 《医学信息(西安上半月)》 2007年第6期1048-1049,共2页 Medical Information
关键词 冠心病 血尿酸 Coronary heart disease Serum uric acid
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参考文献5

  • 1Bickel C,Rupprecht HJ,Blankenherg S.Serum uric acid as an independent predicitor of mortality in patients with angiographically proven coronary artery disease[J].Am J cardiol,2002,89:12.
  • 2Puddu PE,Lanti M,Menott A,et al.Serum uric acid for short-term prediction of cardiovascular disease incidence in the Gubbio population Study[J].Acta Cardio,2001,56:243.
  • 3Bickel C,Rupprecht HJ,Blankenberg S.et al.Serum uric acid as an independent predictor of mortality in patients with angiographically proven coronary artery disease[J].Am J Cardiol,2002,89:12.
  • 4胡健,沈卫峰,张建盛,张大东,张瑞岩,吕安康,张奇,张宪,郑爱芳.冠状动脉内支架置入术后再狭窄与尿酸的关系[J].临床心血管病杂志,2002,18(8):359-360. 被引量:38
  • 5Kuranok,Lkeda H,Oda T,et al.Xanthine oxithine oxidase mediates cyckic flow ariations in a canine model of coronary artery athrommbosis[J].Am J Hpysiol,1996,270:1993.

二级参考文献8

  • 1Fischman D, Leon M,Bain D, et al.A randomized comparison of coronary stent placement and balloon angioplasty in the treatment of coronary disease. N Engl J Med, 1994,331:496-501.
  • 2Savage M P, Fischman D L, Rake R, et al. Efficacy of coronary stenting versus balloon angioplasty in small coronary arteries: Stent restenosis study[STRESS] investigators. J Am Coll Cardiol, 1998,31:307-311.
  • 3Kastrati S, Schomig A, Elezi S, et al. Predictive factors of restenosis after coronary stent placement. J Am Coll Cardiol, 1997,30:1428-1436.
  • 4Erbel R, Haude M, Hopp H W, et al. Restenosis stent(REST) study: Randomized trial comparing stenting and balloon angioplasty for treatment of restenosis after balloon angioplasty(abstract). J Am Coll Cardiol,1996,27(Suppl A):139-143.
  • 5Barbir M, Hunt B J, Galloway D, et al.A randomized pilot trial of low-dose combination lipid-lowering therapy following coronary artery bypass grafting. Clin Cardiol, 1994,17:59-65.
  • 6Loscalzo J, Weinfeld M, Fless G M, et al. Lipoprotein(a), fibrin binding and plasminogen activation. Arteriosclerosis,1990,10:240-245.
  • 7Fang J, Alderman M H. Serum uric acid and cardiovascular mortality. The NHANESI epidemiologic follow-up study, 1971-1992. JAMA, 2000,283:2404-2410.
  • 8郭静萱,毛节明,郭丽君,张福春,李海燕,温尚煜,赵一鸣,陈明哲.冠状动脉内支架再狭窄的多因素回归分析[J].中华心血管病杂志,1998,26(6):423-425. 被引量:33

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  • 1严江涛,汪道文.尿酸与心血管疾病关系的研究进展[J].临床内科杂志,2005,22(1):7-9. 被引量:42
  • 2Pignoli P,Tremoli E,Poli A,et al.Intimal plus medial thicknessof the arterial wall:a direct measurement with ult rasound imaging[J] .Circulation,1986,74:1399.
  • 3GENSINIS GG.A more meaningful scoring system for determining theseverity of coronary heart disease.Am J Cardiol,1983,51(3):606-607.
  • 4CHu NF,Wang DJ,Liou SH,et al.Relationship between hyperuri-cemia and other cardiovascular disease risk factors among adult malesin Taiwan.Eur J Epidemiol 2000:16:13-7.
  • 5Kanishi N,Okamoto M,Yoshida H,et al.Serum uric acid and riskfor development of hypertension and impaired fasting glucose or TypeII diabetes in Japanese male office workers.Eur J Epidemiol 2003:18(6):523-530.
  • 6Lemne C,Jogest rand T,de2Faire U.Carotid intima2media thick-ness and plaque in borderline hypertension[J] .St roke,1995,26(1):34-39.
  • 7Rosa EM,Kramer C,Cast ro I.Association between coronary arteryat herosclerosis and t he intimamedia thickness of the common carotidartery measured on ult rasonography[J] .Arq Bras Cardiol,2003,80(6):589-592,285-288.
  • 8Karpe F,Boquist S,Tang R,et al.Remnant lipoproteins are relat-ed to intimamedia t hickness of t he carotid artery independently ofLDL cholesterol and plasma t riglycerides[J] .J Lipid Res,2001,42(1):17-21.
  • 9Bickel C,Rupprecht HJ,Blankenberg S,et al.Serum uric acid asan independent predictor of mortality in patients with angiographicallyproven coronary artery disease[J] .Am J Cardiol,2002,89(1):12-17.
  • 10Lehto S,Niskanen L,Ronnemaa T,et al.Serum uric acid is astrong predictor of st roke in patient s wit h non insulin dependent di-abetes mellitus[J] .St roke,1998,29(3):635-639.

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