摘要
过氧化物酶体增殖物激活受体(peroxisome proliferator-activatived receptors,PPAR)是由配体激活的转录因子,属于核激素受体超家族。PPAR的激活对调节体内的多种代谢过程有重要的作用。对于多种人体的疾病,以PPAR作为治疗靶点可以取得明显的效果。本文对PPAR的结构及其与疾病的关系作一综述。
Peroxisome proliferator-activatived receptors （PPAR）belong to the nuclear receptor family of ligand-activated transcription factors. PPAR activators can modulate various metabolic pathways in vivo. When PPAR is used as a therapeutic target in many human diseases, significant effects can be obtained. In this paper the structure of PPAR and its relationship with diseases are reviewed.
出处
《国外医学（药学分册）》
2007年第3期200-203,共4页
Foreign Medical Sciences(Section of Pharmarcy)
