22例美洛西林注射液致不良反应文献分析

Mezlocillin Injection-induced Adverse Reactions:Literature Analysis of 22 Cases

目的:探讨美洛西林注射液致不良反应发生的特点。方法:检索《中国医院数字图书馆》,收集1999～2006年7月国内医药学术期刊报道的有关美洛西林注射液致不良反应病例,并进行统计、分析。结论:美洛西林注射液致不良反应临床主要表现为过敏反应,甚至过敏性休克,并以首用即发型和速发型为主。结论:临床应重视美洛西林注射液的过敏反应。

OBJECTIVE： To discuss the manifestation characteristics of mezlocillin injection- induced ADR.METHODS： Mezlocillin injection- induced ADR cases reported in domestic pharmaceutical journals between 1999 and July.2006 were retrieved from China Hospital Digital Libra ry（CHDL）and analyzed statistically.RESULTS：The clinical manifestation of ADR induced by mezlocillin was characterized by allergic reactions or even anaphylactic shock.The major ADR types were firstusing immediate type and the speedy outbreak type. CONCLUSION： Great importance should be attached to allergic reactions induced by mezlocillin injection.