绞股蓝无糖口含片的制备工艺

Preparation Technology of Gynostemma pentaphyllum Buccal Tablet without Sugar

经过筛选处方和优化工艺,采用湿颗粒法研制了新型绞股蓝无糖口含片,并对其质量进行了评价。结果表明,绞股蓝浸膏粉、甜味剂、清凉剂的用量及润湿剂的浓度等因素对口含片的质量有较大影响。当以70%乙醇作润湿剂,15%绞股蓝浸膏粉、77%甘露醇、4%阿斯巴甜为材料,再添加上述混合料总量的0.1%薄荷脑和3%硬脂酸镁,60℃的干燥温度,可制得口感好、有绞股蓝特有风味、表面光滑美观、色泽一致、硬度好、崩解性良好、具有保健功能的新型绞股蓝无糖口含片。

The new Gynostemma pentaphyllm buccal tablet was developed by using damp particle method through selecting formula and optimizing technology, and its quality was evaluated. The result showed that the factors such as the dosage of Gynostemma pentaphyllm extract powder, sweetener, freshener, and humectants concentration had substantial influence on the quality of buccal tablet. With 70% ethanol as moistening agent, when the formula was 15% extract powder of Gynostemma pentaphyllum,77% mannitol and 4% aspartame, adding 0.1% mentha-camphor and 3% magnesium stearate, a new Gynostemma pentaphyllum, buccal tablet without sugar could be obtained, with special favor of Gynostemma pentaphyUm, smooth and good looking surface, good hardness and disintegrability, health-kecping function, color accorded.