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甲状腺激素测定在急性颅脑损伤患者临床应用的评价 被引量:2

Results of clinical application of detection of thyroid hormone in diagnosis of acute cranial injury
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摘要 目的研究急性颅脑损伤患者的甲状腺激素水平变化和临床意义。方法采用化学发光法测定了36例急性颅脑损伤患者血清中的甲状腺激素浓度。结果患者的TT3、FT3、TT4、FT4、TSH浓度分别为(1.3±0.4)nmol/L、(3.1±0.3)nmol/L、(92.4±1.7)nmol/L、(18.6±2.1)nmol/L及(3.9±2.2)nmol/L;患者TT3、FT3血清水平极显著低于正常组(P<0.001)、血清TT4、FT4显著低于正常组(P<0.05),而血清TSH较正常组升高(P<0.05)。同时急性颅脑损伤患组TT3/TT4,FT3/FT4比值低于正常值。结论急性颅脑损伤患者血清TT3、FT3、TT4、FT4和TSH的测定,是观察患者病情及预后的良好指标之一。 Objective To observe the changes of thyroid hormones and analyze its clinical meanings in patients with acute craniocerebral injury. Methods The serum concentrations of thyroid hormones from 88 acute cmniocerebral injury patients were measured by chemiluminescent autoanalyzer. Results The concentrations of TT3 ( 1.3±0.4nmol/L), FT3 (3.1 ± 0.3nmol/L), TT4(92.4 ±1.7nmol/L) and FT4 (18.6± 2.1 mnol/L) in patients were decreased as compared to that in normal controls (P 〈 0. 05), the changes of T3,FT3 were more significant, while the level of TSH(3.9±2.2nmol/L) was higher than that in normal controls ( P 〈 0.05). The values of TT3/TT4 and FT3/FT4 were lower than that in normal controls. Conclusion The serum concentrations of TT3, FT3, TT4, FT4 and TSH in patients with acute craniocerebral injury are one of the best means to observe the state of an illness and evaluate its prognosis.
出处 《中国热带医学》 CAS 2007年第8期1338-1339,共2页 China Tropical Medicine
关键词 颅脑损伤 甲状腺激素 病情观察 Craniocerebral injury Thyroid hormones Observing the state of an illness
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