射干、金银花等八种中药抗真菌实验研究

Antifungal effects of eight kinds of traditional Chinese medicine in vitro

目的:体外观察射干、金银花等8种中药对新型隐球菌、镰刀、白色念珠菌、曲霉等临床分离的9种致病真菌的作用。方法:本实验应用试管法对射干、金银花、土槿皮、蛇床子、苦参、虎杖、黄连、黄岑等八种中药对9种临床分离的致病性真菌的抗真菌作用进行了研究。结果:射干的最小抑菌浓度MIC:25 mg/ml,金银花的MIC:100 mg/ml,土槿皮的MIC:25 mg/ml,蛇床子的MIC:25 mg/ml,苦参的MIC:25 mg/ml,虎杖的MIC:25 mg/ml,黄连的MIC:200 mg/ml,黄岑的MIC:12.5 mg/ml,黄连对9种致病真菌无作用外,其余7种中药均对9种致病真菌均有疗效。结论:中草药抗真菌效果较好,为临床治疗提供了依据。

Objective： The antifungal effect of eight kinds of traditional Chinese medicine were studied in vitro. Methods： Fungi were cul tured in the sabourauds. Results： It was showed that： MIC minimal inhibitory concentration of scutellaria baicalensis georgi for belamcanda chinensis. MIC： 25 mg/ml; Lonicera japonia Thumb MIC： 100 mg/ml; psudolarix kaempferi MIC： 25 mg/ml; cnidium monnieri MIC： 25 mg/ml; sophora flavesens MIC- 25 mg/ml; polugonum cuspidatum siebzuccMIC： 25 mg/ml; coptis chinensis MIC： 200 mg/ml; scutellaria baicalensis georgi MIC： 12, 5 mg/ml. Conclusion： Compound eight solution might be used for the treatment of dermatosis. Eight can inhibit fungi growth effectively.