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肺癌患者血浆D-二聚体异常改变的双重意义 被引量:13

Double Significance of Plasma D dimer Abnormal Changes in Lung Cancer Patients
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摘要 本文检测了102例肺癌患者血浆D-二聚体(D-dimer,D-D)浓度,为探讨D-D在肺癌转移和预后中的意义,把病人分为三组:原发肿瘤组(T组),淋巴结转移组(N组),远处器官转移组(M组)。结果:各组D-D浓度均显著高于对照组(P<0.01),且各组间差异非常显著(P<0.01,随病情加重,转移发生,D-D浓度呈递增趋势,T组<N组<M组。在M组中,100%病例D-D浓度异常升高。实验表明:D-D浓度的异常升高,不仅意味着患者血粘度升高,纤溶活性增加,在肿瘤病人持续升高,还提示患者预后不良,容易发生癌转移。可作为判断预后指标之一。 The plasma D dimer(D D) concentrations were detected in 102 lung cancer cases.The patients were divided into tumor group (t group),lymph node metastasis group(N group),and organ metastasis group(M group).The results showed that the D D level of all patients group was significantly higher than the normal control group( P <0 01) and there were differences among the each group of patientsd the remarkably D D levels increased in the developing cases and occurrence of the metastasis one.sorting the levels was T group<N group<M group.Especially,D D abnormal increased in the all cases of M group.Theses results were concluded that the D D level abnormal increasing not only meaning the patients with a higher viscosity and fibriolysic.active,but also indicted the bad progresses and the more possibility of meatstasis when it rises continually.
出处 《中国慢性病预防与控制》 CAS 1997年第2期73-74,共2页 Chinese Journal of Prevention and Control of Chronic Diseases
关键词 肺肿瘤 D-二聚体 Lung cancer D dimer\ Tumor metastasis
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