复方甘草酸苷治疗新生儿高胆红素血症疗效观察

Observation on Therapeutic Efficacy of Compound Glycyrrhizin for Neonatal Hyperbilirubinemia

目的:观察复方甘草酸苷治疗新生儿高胆红素血症的疗效。方法:198例新生儿高胆红素血症患儿随机分为治疗组100例(儿科常规治疗+复方甘草酸苷)与对照组98例(儿科常规治疗),2组疗程均为7d。结果:治疗组与对照组总有效率分别为97.0%、75.5%,治疗组明显优于对照组(P<0.05)。结论:复方甘草酸苷治疗新生儿高胆红素血症安全、有效,降黄较快。

OBJECTIVE： To observe the therapeutic efficacy of compound glycyrrhizin in the treatment of neonatal hyperbilirubinemia.METHODS：A total of 198 pediatric patients with neonatal hyperbilirubinemia were randomly assigned to receive pediatric conventional therapy plus compound glycyrrhizin（trial group, n ： 100） or pediatric conventional therapy alone （control group, n = 98） for 7 days.RESULTS： The total effective rate in trial group was 97.0%, significantly higher than in control group（75.5% ） （P 〈 0.05） .CONCLUSION： Compound glycyrrhizin is safe and effective for neonatal hyperbilirubinemia,and it can subside jaundice quickly.