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双黄连抑制甲1型流感病毒诱导细胞凋亡的机制研究 被引量:14

Mechanism of Shuanghuanglian in Inhibiting Apoptosis of Hela Cells Induced by Influenza Virus A1
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摘要 目的:研究双黄连抑制甲1型流感病毒诱导细胞凋亡的机制。方法:将宫颈癌(Hela)细胞分成4组:病毒对照组、实验组、细胞对照组、药物对照组,采用流式细胞术计算细胞凋亡的百分率。结果:实验组细胞凋亡的百分率与病毒对照组比较有非常显著性差异(P<0.01)。结论:双黄连可抑制甲1型流感病毒诱导Hela细胞凋亡。 OBJECTIVE: To investigate the mechanism of Shuanghuanglian in inhibiting the apoptosis of Hela cells induced by influenza virus A1. METHODS: The Hela cells were divided into 4 groups: virus control group, test group, cell control group, and drug control group.The percentage of apoptotic Hela cells was calculated through flow cytometry. RESULTS: Significant differences were noted in the percentage of apoptotic Hela cells between virus control group and the test group(P 〈 0.01) . CONCLUSION: This study showed that Shuanghuanglian could inhibit the apoptosis of Hela cells induced by influenza virus A1.
出处 《中国药房》 CAS CSCD 北大核心 2007年第27期2086-2088,共3页 China Pharmacy
基金 江西省自然科学基金资助项目(0540131)
关键词 流感病毒 凋亡 流式细胞术 宫颈癌细胞 双黄连 Influenza virus Apoptosis Flow cytometry Hela cell Shuanghuanglian
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