摘要
A case of a 53-year-old female patient with reactive lymphoid hyperplasia （RLH）, clinically designated as pseudolymphoma of the liver is described in this article. The patient was admitted to our hospital for further evaluation of hepatic tumors incidentally discovered at another hospital. Various diagnostic methods, including ultrasonography （US）, computerized tomography （CT）, magnetic resonance imaging （MRI） and hepatic angiography displayed three small lesions in the liver with outstanding findings consistent with hepatocellular carcinoma （HCC）. Surgical resection was performed and the three lesions were microscopically diagnosed as RLH of the liver. The lesions comprised a massive infiltration of lymphoid cells with follicles and hyalinized inter- follicular spaces. Immunohistochemical examination revealed that infiltrating lymphocytes had no prominent nuclear atypia and polyclonality. RLH of the liver is a very rare condition and only twelve cases have been reported in the English literature. Majority of the reported cases were middle-aged women and about half of them had some immunologic abnormalities such as autoimmune thyroiditis, Sjogren＇s syndrome, primary immunodeficiency, primary biliary cirrhosis. Since they are olden clinically misdiagnosed as HCC, surgery is the choice of treatment for these patients. Although their pathology resembles malignant lymphoma, the clinical course is completely benign. The authors propose that RLH of the liver can be discriminated from HCC by its clinical features.
有反应淋巴的增生(RLH ) 的一个 53 岁的女病人的一个盒子，肝的临床上指明的同样假的淋巴瘤在这篇文章被描述。病人为顺便说一下在另一所医院发现的肝的肿瘤的进一步的评估进入我们的医院。各种各样的诊断方法，包括的 ultrasonography (美国) ，计算机化的断层摄影术(CT ) ，磁性的回声成像(MRI ) 和肝的血管造影术与与肝细胞癌(HCC ) 一致的突出的调查结果在肝显示了三小损害。外科的切除术被执行，三损害是作为肝的 RLH 诊断的用显微镜。损害与滤泡和 hyalinized 包括了淋巴样细胞的巨大的渗入内部小囊的空格。Immunohistochemical 检查表明渗透的淋巴细胞没有突出的原子非典型和 polyclonality。肝的 RLH 是一个很稀罕的条件，仅仅 12 个案例在英语文学被报导了。报导案例的多数是中年的女人并且关于他们的一半有象自体免疫的甲状腺炎那样的一些免疫逻辑畸形， Sjogren 的症候群，主要免疫不全，主要胆汁性肝硬变。因为他们临床上经常作为 HCC 被误诊，外科是为这些病人的治疗的选择。尽管他们的病理类似于恶性淋巴瘤，临床的功课是完全良性的。作者建议肝的 RLH 能被它的临床的特征从 HCC 区别。
