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清远市小学学生SARS冠状病毒抗体血清流行病学研究

Serum Epidemiological Research on SARS Coronavirus Antibody among Pupils in Qingyuan City
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摘要 目的了解清远市小学学生SARS冠状病毒(简称SARS-CoV)抗体水平。方法分别于2005年10月和2006年4月,采集清远市2所乡镇小学学生及2003年SARS-CoVIgG检测阳性儿童的血液,用酶联免疫法检测血清中SARS-CoV抗体IgG。结果共检测小学学生血清样本449份,SARS-CoV IgG总阳性率为1.78%(8/449),男、女学生之间阳性率差异无统计学意义(P>0.05);其中在9、10、11、12岁年龄组学生中检出SARS-CoV IgG,阳性率分别为2.70%(1/37)、7.58%(5/66)、2.13%(1/80)、0.99%(1/101),4个年龄组阳性率比较,差异无统计学意义(P>0.05);8份SARS-CoV IgG阳性血清样本均来自同一学校;对17名2003年SARS-CoV lgG检测阳性的儿童进行追踪重新采血检测,阳性率为11.76%(2/17)。结论该地区小学学生SARS-CoV抗体阳性率较低,存在隐性感染及聚集现象,SARS-CoV抗体IgG水平随时间延长会逐渐下降,甚至消火。 [ Objective ] To learn the antibody level of SARS coronavirus among the pupils in Qingyuan City. [ Methods ] Blood samples of the pupils and SARS CoV IgG positive children in 2003 were collected in Dec. 2005 and Apr. 2006 respectively and detected with ELISA for the SARS CoV IgG. [ Results] The total positive rate of SARS CoV IgG of the 449 serum samples was 1.78% (8/449 ) , no significant difference was found between males and female students ( P 〉 0. 05) ; the positive rates in the 9, 10, 11 and 12 age groups were 2.70% ( 1/37) , 7.58% (5/66 ) , 2.13% (1/80) and 0.99% ( 1/101 ) respectively, which had no signif icant difference (P 〉 0.05 ) ; all the 8 SARS CoV IgG positive serum samples were collected from the same school ; the follow - up detection for the SARS CoV IgG positive in 2003 showed that the positive rate of them was 11.76% ( 2/17). [ Conclusion] The positive rate of SARS CoV antibody IgG is proved to be low among the pupils in this area, but concessive infection and aggregation of SARS still exist; the level of SARS CoV antibody will gradually decline or even diminish as time goes by.
出处 《职业与健康》 CAS 2007年第24期2295-2296,共2页 Occupation and Health
关键词 SARS冠状病毒 血清学 抗体 SARS Coronavirus Serology Antibody
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