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胃、结直肠癌术后良、恶性肠梗阻病因分析 被引量:7

Analysis of benign and malignant bowel obstruction in patients previously operated for gastric and colorectal cancer
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摘要 目的:探讨胃癌、结直肠癌手术后肠梗阻的原因。方法:对手术探查的68例胃癌、结直肠癌术后肠梗阻的病例进行回顾性分析,探讨良、恶性原因所致肠梗阻在发生时间、病理、临床表现及癌胚抗原(CEA)的特点。结果:良、恶性肠梗阻分别占55.9%(38/68)和44.1%(30/68)。76.3%(29/38)的良性肠梗阻发生在术后6个月以内,恶性肠梗阻83.3%(25/30)出现在术后6个月以后,差异有统计学意义(P<0.01)。原发肿瘤分化较差、分期较晚者更多发生恶性肠梗阻(P<0.05);良性肠梗阻更多表现为完全性肠梗阻,且血清CEA平均水平和阳性率较恶性肠梗阻低(P<0.05)。结论:胃癌、结直肠癌术后发生肠梗阻可根据初次手术时间结合临床特点、原发肿瘤病理及CEA大致判断为良、恶性原因所致。 Objective: To investigate the causes of patients for bowel obstruction (BO) after operation for gastric and colorectal cancer. Methods. From 1992 to 2006,data of 68 patients undergoing laparotomy for BO after operation for gastric and colorectal cancer were analysed retrospectively. The characteristics of patients of time,pathology, clinical appearance and serum level of carcinoembryonic antigen (CEA) causing by benign and malignant etiology were determined. Results: the BO causing by benign and malignant etiology were 55.9% (38/68) and 44.1% (30/68) respectively. For benign bowel obstruction ( BBO)76.3% (29/38) of cases occurred within 6 months. While 83.3% (25/30) of malignant bowel obstruction (MBO) occurred more than 6 months. The differences between them were significant( P 〈 0.01 ) . The MBO were more occurred with lower differentiation and later staging compared with BBO(P 〈 0. 05) ;Complete obstruction were more observed in BBO compared with MBO( P 〈 0.01 ), positive rate of serum CEA in BBO as well as the mean level of CEA were lower than that in MBO( P 〈 0.01 ). Conclusion: All the characteristics and factors mentioned above could be used in etiological diagnosis of BO after operation for gastric and colorectal cancer.
出处 《现代肿瘤医学》 CAS 2007年第5期672-674,共3页 Journal of Modern Oncology
关键词 胃肠道肿瘤 肠梗阻 术后 病因 gastrointestinal carcinoma bowel obstruction postoperation etiology
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参考文献5

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