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缬沙坦对原发性高血压老年患者大动脉弹性的影响 被引量:3

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摘要 目的探讨血管紧张素Ⅱ受体拮抗剂缬沙坦对老年高血压患者大动脉弹性的影响。方法选择40例正在规律服用降压药物治疗老年高血压患者,分为对照组(20例,服安慰剂1片/d)和缬沙坦组(20例,服缬沙坦氟80mg/d),采用自动脉搏波传导速度测定仪检测治疗前和治疗12周后患者的颈动脉至股动脉脉搏波传导速度(C-FPWV),以判断其大动脉弹性变化。结果与治疗前相比,治疗12周后患者的收缩压、脉压、平均压、C-FPWV及舒张压显著降低(P<0.05~P<0.01)。结论缬沙坦不仅能良好地控制血压,亦能明显改善大动脉弹性功能。
作者 赵文杰
出处 《实用心脑肺血管病杂志》 2007年第10期767-768,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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