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免疫组化结合连续切片检测舌癌阴性淋巴结的微转移

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摘要 【目的】探讨一种检测舌癌患者阴性淋巴结微转移的方法。【方法】用免疫组化结合连续切片对60例舌癌患者的264枚常规病理检测阴性淋巴结进行微转移检测。微转移阳性标准:单个阳性反应细胞或数个阳性反应细胞散在分布,或数个阳性反应细胞成簇分布形成转移灶但直径小于0.5mm,并且复查所有阳性结果的原 HE 切片证实无转移癌存在。【结果】微转移多数分布于淋巴窦内,少数位于生发中心,呈单个或数个散在阳性细胞,具有明显的异型性。60例舌癌患者的264枚常规病理检测阴性淋巴结共有18枚(6.82%)淋巴结和14例(23.3%)患者证实存在微转移。【结论】用免疫组化结合连续切片进行舌癌患者阴性淋巴结微转移检测是一种比较可靠实用的方法。
出处 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2005年第B03期41-42,共2页 Journal of Sun Yat-Sen University:Medical Sciences
基金 广东省科技计划资金资助(2003C50113)
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