期刊文献+

链霉菌真核型丝氨酸/苏氨酸蛋白激酶的研究进展 被引量:5

An update of Streptomyces eukaryotic-type Ser/Thr protein kinases—A Review
下载PDF
导出
摘要 简要回顾了丝/苏氨酸蛋白激酶在链霉菌中的发现过程,详细介绍了链霉菌中几个研究较为深入的丝/苏氨酸蛋白激酶的功能,同时对天蓝色链霉菌Streptomyces coelicolor A3(2)和除虫霉菌Streptomyces avermitilis MA-4680中的丝/苏氨酸蛋白激酶的跨膜种类和蛋白结构域特点作了初步的生物信息学分析。 We review briefly the strategies and processes to identify Ser/Thr protein kinases from Streptomycesspp. and discussed in detail the functions of well studied Ser/Thr protein kinases, such as the AfsR-kinase(AfsK), We used bioinformatic methods to predict transmembrane regions in Ser/Thr protein kinases of S. coelicolor A3(2) and S. avermitilis. The complete sets of Ser/Thr protein kinases from genomes of Streptomyces coelicolor A3(2) and Streptomyces avermitilis MA-4680 were categorized based on domain analyses.
出处 《微生物学报》 CAS CSCD 北大核心 2008年第1期126-131,共6页 Acta Microbiologica Sinica
关键词 丝氨酸/苏氨酸蛋白激酶 链霉菌 结构域 调节 Ser/Thr protein kinases Streptomyces domain regulation
  • 相关文献

参考文献34

  • 1Wang JY, Koshland DE Jr. Evidence for protein kinase activaties in the prokaryote salmonella typhimurium. J Biol Chem, 1978, 253(21): 7605-7608.
  • 2Munoz-Dorado J, Inouye S, Inouye M. A gene encoding a protein serine/threonine kinase is required for normal development of M. xanthus, a gram-negative bacterium. Cell, 1991,67(5): 995-1006.
  • 3Petr i ckov a K, Petr i cek M. Eukaryotic-type protein kinases in Streptomyces coelicolor: variations on a common theme. Microbiology, 2003, 149(7): 1609-1621.
  • 4Gonzalez L, Phalip V, Zhang CC. Characterization of PknC, a Ser/Thr kinase with broad substrate specificity from the cyanobacterium Anabaena sp. strain PCC 7120 Eu r J Biochem, 2001,268(6): 1869-1875.
  • 5Han G, Zhang CC. On the origin of Ser/Thr kinases in a prokaryote. FEMS Microbiol Lett, 2001,200(1 ):79-84.
  • 6Rajagopal L,Vo A,Silvestroni A, et al. Regulation of purine biosynthesis by a eukaryotic-type kinase in Streptococcus agalactiae. Mol Microbiol, 2005, 56(5): 1329-1346.
  • 7Hanks SK. Genomic analysis of the eukaryotic protein kinase superfamily: a perspective. Genome Biol, 2003, 4(5): 111.
  • 8Matsumoto A, Hong SK, Ishizuka H, et al. Phosphorylation of the AfsR protein involved in secondary metabolism in Streptomyces species by a eukaryotic-type protein kinase. Gene, 1994, 146(1): 47-56.
  • 9Urabe H, Ogawara H. Cloning, sequencing and expression of serine/threonine kinase -encoding genes from Streptomyces coelicolor A3(2). Gene, 1995, 153(1): 99-104.
  • 10Hirakata T, Kieser H, Hopwood D, et al .Putative protein serine/threonine kinase genes are located in several positions on the chromosome of Streptomyces coelicolor A3(2). FEMS Microbiol Lett, 1998, 159(1): 1-5.

二级参考文献26

  • 1[1]Beppu T. Signal transduction and secondary metabolism:prospects for controlling productivity. [J]. TIBTECH,1995,13:264
  • 2[2]Cozzone AJ. Protein phosphorylation in prokaryotes. [J].Annu Res Microbiol, 1988, 42 : 97
  • 3[3]Munoz-Dorado J, Inouye M, Inouye S. A gene encoding protein serin/threonine kinase is required for normal development of M. xanthus, a Gram-negative bacterium.[J]. Cell,1991, 67:995
  • 4[4]Perrand A-L, Weiss V, Gross R. Signalling pathways in two component phosphorelay systems. [J]. Trends Microbiol, 1999,7:115
  • 5[5]Alex LA, Sinon MI. Protein kinase and signal transduction in prokaryotes and eukaryotes. [J]. Trend Genet,1994,10:133
  • 6[6]Zhang CC. Bacterial signalling involving eukaryotic-type protein kinase. [J]. Mol Microbiol, 1996,20 (1): 9
  • 7[7]Matsumoto A, Hong S-K, Ishizuka H, et al. Phosphorylation of the AfsR protein involved in secondary metabolism in Streptomyces species by a eucaryotic-type protein kinase. [J]. Gene, 1994,146: 47
  • 8[8]Hong S-K,Matsumoto A, Horinouchi S, et al. Effects of protein kinase inhibitors on in vitro protein phosphorylation and cellular differentiation of Streptomyces griseus.[J].Mol Gen Genet,1993,263:347
  • 9[9]Horinouchi S, Kito M, Nishiyama M, et al. Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces colicolor A3 (2). [J]. Gene,1990, 95:49
  • 10[10]Vogtli M, Chang P-C, Cohen SN. afsR2: a previously undetected gene encoding a 63-amino-acid protein that stimulates antibiotic production in Streptomyces lividans.[J]. Mol Microbiol, 1994,14: 643

共引文献1

同被引文献75

引证文献5

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部