阿奇霉素治疗小儿支原体肺炎临床疗效

Clinical therapeutic effect of azithromycin for treatment of children with mycoplasmal pneumonia

目的探讨阿奇霉素治疗支原体肺炎(MP)的临床疗效。方法42例MP患儿分为阿奇霉素治疗组(n=27)和红霉素治疗组(n=15),对2组临床有效率、临床症状体征消失时间、住院时间、药物不良反应等进行比较。结果阿奇霉素组有效率(92.3%)明显高于红霉素组(66.7%,2χ=7.059,P<0.05);阿奇霉素组体温恢复正常时间、咳嗽消退时间及住院时间均短于红霉素组(P<0.05)。阿奇霉素组胃肠道反应和局部疼痛少于红霉素组(P<0.05)。结论阿奇霉素治疗MP具有快速、高效、方便等优点,患儿依从性好。

Objective To investigate the clinical therapeutic effect of azithromyci for treatment of children with mycoplasmal pneumonia（MP）. Methods Forty-two children with MP were divided into azithromycin group （ n = 27 ） and erythrocin group（ n = 15 ）,the clinical effective rate, clinical symptom extinction time, length of stay and drug adverse reaction were compared between two groups. Results The clinical effective rate of azithromycin group（92.3% ） was higher than this of erythrocin group（66.7% ,Х^2 = 7. 059 ,P 〈 0.05）. The time of body temperature returned to common, cough regression and hospital day in azithromycin group were all less than the erythromycin groups＇（ P 〈 0.05 ）. The incidence rates of gastrointestinal reaction and local pain were lower in azithromycin group than these in erythrucin group （ P 〈 0.05 ）. Conclusion It have quickly, high-performance and convenient merits that MP were treated with azithromycin, and have good compliance for children.