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罗格列酮对兔动脉粥样硬化心血管系统超微结构的影响 被引量:2

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摘要 目的观察罗格列酮对兔动脉粥样硬化(AS)的心血管系统保护作用。方法大耳白兔37只,随机分为空白对照组、AS组和罗格列酮组.空白对照组饲喂普通饲料,其余组给与高脂饮食,罗格列酮组饲料中加入罗格列酮,应用电镜观察三组内皮细胞、平滑肌细胞等结构。结果AS兔主动脉、颈动脉的动脉壁内膜等很多异常部分,经罗格列酮治疗后,得到显著改善。结论罗格列酮对兔AS模型心血管系统超微结构的异常有纠正或改善作用。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2008年第4期342-344,共3页 Chinese Journal of Gerontology
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