维吾尔族、汉族幽门螺杆菌感染的检出率对比分析

Analysis of helicobacter pylori detection rate in Uygur and chinese duodenum disease

目的:了解维吾尔族、汉族患者慢性胃炎和消化性溃疡病中幽门螺旋杆菌(H.pylori,Hp)感染的检出率,为临床诊疗和防治Hp感染提供理论依据。方法:对309例维吾尔族、汉族患者进行尿素酶试验和Giemsa染色诊断Hp的感染,比较维吾尔族、汉族患者在不同疾病、年龄、性别中Hp感染情况等。结果:(1)维吾尔族患者慢性胃炎(CG)中Hp阳性率44.59%(33/74),汉族患者CG中Hp阳性率44.06%(52/118),差异无统计学意义(χ2=0.005,P=0.943)。(2)维吾尔族患者十二指肠溃疡(Du)中Hp阳性率41.18%(14/34),汉族患者Du中Hp阳性率52.50%(21/40),差异无统计学意义(χ2=0.945,P=0.331)。(3)维吾尔族患者胃溃疡(Gu)中Hp阳性率55.00%(11/20),汉族患者Gu中Hp阳性率27.27%(6/22),差异无统计学意义(χ2=3.343,P=0.067)。结论:维吾尔族、汉族患者慢性胃炎和消化性溃疡病中Hp感染的检出率无明显差异。对于维吾尔族、汉族慢性胃炎和消化性溃疡病的患者均需检查Hp有无感染。

Objective： To study Helicobacter pylori infection rate in Uygur and Hhan patients with gastroduodenum disease, provide theory idea to H. pylori detection and eradication in clinical medicine. Method： Serodiagnosis for determining H. pylori infection status by H. pylori RUT and Giemsa stain examination for 309 Han and Uygur patients were done. If H. pylori RUT and Giemsa stain all positive, this was regarded as H. pylori positive. Compared Han and Uygur patients with H. pylori infection rate, age, gender. Results： The duodenal ulcer （Du） patients were more younge and gastric ulcer （Gu） patients more olden compare with chronic gastritis （CG） patients. （1） The H. pylori positive rate were 44.06%（52/118） in Han nationality with CG patients, and 44.59.% （33/74） in Uygur nationality with CG patients. There was no statistically significance （χ^2 =0. 005, P=0. 943）. （2） The H. pylori positive rate was 52.50%（21/ 40） in Han nationality with Du patients, 41.18%（14/34）in Uygur nationality with Du patients. There was no statistically significance （χ^2=0. 945, P=0. 331）. （3） The H. pylori positive rate was 27. 27%（6/22） in Han nationality with Gu patients, 55.00%（11/20） in Uygur nationality with Gu patients. There was no statistically significance （χ^2 =3. 343, P =0. 067）. Conclusion： As can be seen from the study, we believe that there are no significance in H. pylori positive rate in Han and Uygur patients. Identical H. pylori exam method and therapy strategy can be used to all same Uygur and Chinese gastro-duodenum disease.