摘要
目的:研究氨溴索针剂对慢性阻塞性肺疾病(COPD)急性加重期患者氧化与抗氧化能力的影响。方法:COPD急性加重期患者,采用氨溴索针剂治疗,检测患者血清丙二醛(MDA)、超氧化物歧化酶活性(SOD)水平。并比较两组患者总有效率。结果:氨溴索治疗显著降低患者血清MDA含量,显著增加SOD水平,总有效率提高。结论:氨溴索能减轻COPD急性加重期患者氧化应激程度,提高患者抗氧化能力,对COPD患者有一定辅助治疗价值。
Objective:To investigate the effect of ambroxol on oxidative stress in the patients with chronic obstructive pulmonary disease(COPD). Methods:Patients with COPD were treated with ambroxol. The levels of serum MDA and SOD were determined. Results:After the application of ambroxol,MDA content decreased significantly,and the level of SOD increased significantly.Conclusion:Ambroxol treatment could ameliorate the oxidative stress in the patients with COPD.
出处
《现代医药卫生》
2008年第5期654-655,共2页
Journal of Modern Medicine & Health