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氨溴索对慢性阻塞性肺疾病患者氧化应激的影响 被引量:7

Effect of ambroxol on oxidative stress in the patients with COPD
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摘要 目的:研究氨溴索针剂对慢性阻塞性肺疾病(COPD)急性加重期患者氧化与抗氧化能力的影响。方法:COPD急性加重期患者,采用氨溴索针剂治疗,检测患者血清丙二醛(MDA)、超氧化物歧化酶活性(SOD)水平。并比较两组患者总有效率。结果:氨溴索治疗显著降低患者血清MDA含量,显著增加SOD水平,总有效率提高。结论:氨溴索能减轻COPD急性加重期患者氧化应激程度,提高患者抗氧化能力,对COPD患者有一定辅助治疗价值。 Objective:To investigate the effect of ambroxol on oxidative stress in the patients with chronic obstructive pulmonary disease(COPD). Methods:Patients with COPD were treated with ambroxol. The levels of serum MDA and SOD were determined. Results:After the application of ambroxol,MDA content decreased significantly,and the level of SOD increased significantly.Conclusion:Ambroxol treatment could ameliorate the oxidative stress in the patients with COPD.
作者 梁雄 马育霞
出处 《现代医药卫生》 2008年第5期654-655,共2页 Journal of Modern Medicine & Health
关键词 氧化应激 氨溴索 慢性阻塞性肺疾病 Oxidative stress Ambroxol COPD
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参考文献6

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