肺心病发作期患者中医证类与血清类洋地黄因子含量相关性研究

Study on the Correlation Between TCM Syndrome Types and the Content of sEDF in Patients with Acute Attack or Chronic Pulmonary Heart Disease(CPHD)

以放免法规定60例不同中医证类慢性肺心病急性发作期患者血清美洋地黄因子（sEDF）含量，探讨两者之间的内在关系。研究结果表明，肺心病组sEDF含量比正常人对照组明显升高（P＜0．0001）。属于阳虚水泛型组的sEDF含量明显高于痰浊阻肺组（P＜0．001）。经治疗后，前组患者sEDF含量比后组患者下降显著，提示肺心病急性发作期患者sEDF含量变化可作为该病中医证类分型的重要依据之一，为实现中医证类标准化提供了一个新的实验室依据。

The puopse of this study is to explore the relationship between TCM syndrome types and the content of sEDF in patients with acute attack of CPHD. The content of sEDF was determined by radheimmunoassay in 60 cases with different TCM syndromes. The results showed that the content of sEDF in CPHD group was significantly higher than that of healthy people group (P<0. 0001). The content of sEDF in group with edema due to yang deficiency was significantly bigher than that of group with acculmulation of phlegm-damp in the lung(p w<0. 001). It had been markedly reduced after treatment in former group than in the latter group, suggesting that the changes of the sEDF content can be regard as one of the important basis of differentiation of TCM syndrome types of this disease. It provided a new experimental method to achieve the standardhation of TCM syndromes.