摘要
Dendritic cells(DCs),representing a heterogenous population of professional antigen-presenting cells,are the initiators and modulators of the immune responses.Studies indicate that regulatory T cells contribute to immune nullipotency and immune suppression via cell-cell contact or cytokine secretion.These two kinds of cells may be valuable tools for modulating immunity in the setting of autoimmunity,cancer,chronic viral infections and graft rejection,etc.Here we discuss the current knowledge on the functions of regulatory T cells and denditic cells-based immunoregulation and the applications.
Dendritic cells （ DCs）, representing a heterogenous population of professional antigen - presenting cells, are the initiators and modulators of the immune responses. Studies indicate that regulatory T cells contribute to immune nullipotency and immune suppression via cell - cell contact or cytokine secretion. These two kinds of cells may be valuable tools for modulating immunity in the setting of auto - immunity, cancer, chronic viral infections and graft rejection, etc. Here we discuss the current knowledge on the functions of regulatory T cells and denditic cells - based immunoregulation and the applications.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2008年第3期610-616,共7页
Chinese Journal of Pathophysiology
基金
国家重点基础研究发展规划资助项目(No.2005CB522602)
国家杰出青年科学基金资助课题(No.30125020)
关键词
树突细胞
调节性T细胞
免疫调节
Dendritic cells
Regulatory T cells
Immunoregulation
