摘要
[目的]观察硝苯地平对慢性阻塞性肺病(COPD)的近期疗效。[方法]用临床对比分析法的设计方法,观察硝苯地平对COPD患者[一秒钟用力呼气容积(FEV1)/用力肺活量(FVC)﹤70%]的近期疗效。在70例患者中,治疗组36例(硝苯地平10~20mg,每日3次),对照组34例(常规综合治疗)。[结果]两组均衡性检验有可比性;应答率比较:治疗组总有效率94.5%,对照组82.3%,治疗组明显高于对照组,两组差异有统计学意义(P﹤0.05);FEV1和动脉血二氧化碳分压(PaCO2)恶化不明显(P﹥0.05)。[结论]本文结果显示硝苯地平用于阻塞性肺病(COPD)的辅助治疗,获显著疗效。
[ Objective] To observe the short-term curative effect of nifedipine on the treatment of chronic obstructive pulmonary tuberculosis (COPD). [Methods] Used clinical contrastive analysis method, observed the short-term curative effect of nifedipine on treatment of COPD patients [forced expiratory volume per second (FEV1)/forced vital capacity (FVC) 〈 70%]. There were 70 patients, treatment group 36 cases used nifedipine 10-20rag ter die, control group 34 cases used routine and combined therapy. [ Results] Balanced examinations in two groups had the comparability. Compared the response rates: total effective rate was in the treatment group was 94.5%, which in the control group 82.3%. The total effective rates was obviously higher in the treatment group than that in the control group, the difference was significant (P 〈 0.05) : the aggravations of FEV1 and arterial partial pressure of carbon dioxide (PaCO2) were not obvious (P 〉 0.05). [Conclusion] The results show that the effects of nifedipine on the adjunctive treatment of COPD are remarkable.
出处
《现代预防医学》
CAS
北大核心
2008年第7期1368-1369,共2页
Modern Preventive Medicine
基金
湖南省卫生厅科研基金资助(B2007199)
关键词
硝苯地平
阻塞性肺病
近期疗效
Nifedipine
Obstructive pulmonary disease
Short-term curative effect